Pesticidal 3-aryl-pyrrolidine-2,4-diones

ABSTRACT

Insecticidal, acaricidal, herbicidal and antimycotic 3-aryl-pyrrolidine-2,4-diones of the formula ##STR1## in which X represents alkyl, halogen or alkoxy, 
     Y represents hydrogen, alkyl, halogen, alkoxy or halogenoalkyl, 
     Z represents alkyl, halogen or alkoxy, 
     n represents a number from 0-3, 
     R represents hydrogen or represents the groups --CO--R 1  or --CO--O--R 2 , 
      in which 
     R 1  represents alkyl, alkenyl, alkoxyalkyl, alkylthioalkyl, polyalkoxyalkyl or cycloalkyl which can be interrupted by hetero atoms, each of which radicals is optionally substituted by halogen, or represents optionally substituted phenyl, optionally substituted phenylalkyl, substituted hetaryl, substituted phenoxyalkyl or substituted hetaryloxyalkyl, or represents optionally substituted phenyl, optionally substituted phenylalkyl, substituted hetaryl, substituted phenoxyalkyl and substituted hetaryloxyalkyl, and 
     R 2  represents alkyl, alkenyl, alkoxyalkyl, polyalkoxyalkyl or optionally substituted phenyl or cycloalkyl, each of which radicals is optionally substituted by halogen, 
     A represents alkyl, alkenyl, alkinyl, alkoxyalkyl, polyalkoxyalkyl, alkylthioalkyl, or cycloalkyl which is optionally interrupted by a hetero atom, each of which radicals is optionally subsituted by halogen, or represents arylalkyl which is optionally substituted by halogen, alkyl, halogenoalkyl, alkoxy or nitro, 
     B and C* independently of one another represent hydrogen, alkyl or alkoxyalkyl.

This is a division of application Ser. No. 460,208, filed Jan. 2, 1990, now U.S. Pat. No. 5,045,560.

The invention relates to new 3-aryl-pyrrolidine-2,4-dione derivatives, to several processes for their preparation, and to their use as insecticides, acaricides and herbicides.

Pharmaceutical properties have previously been described of 3-acyl-pyrrolidine-2,4-diones (S. Suzuki et al. Chem. Pharm. Bull. 15 1120 (1967)). Furthermore, N-phenylpyrrolidine-2,4-diones were synthesized by R. Schmierer and H. Mildenberger Liebigs Ann. Chem. 1985 1095. A biological activity of these compounds has not been described.

Compounds of a similar structure (3-aryl-pyrrolidine-2,4-diones) are disclosed in EP-A 0,262,399, but a herbicidal, insecticidal or acaricidal action is not known in these cases.

New 3-aryl-pyrrolidine-2,4-dione derivatives have now been found, which are represented by the formula (I) ##STR2## in which X represents alkyl, halogen and alkoxy,

Y represents hydrogen, alkyl, halogen, alkoxy and halogenoalkyl,

Z represents alkyl, halogen and alkoxy,

n represents a number from 0-3,

R represents hydrogen or represents the groups --CO--R¹, --CO--O--R²

in which

R¹ represents alkyl, alkenyl, alkoxyalkyl, alkylthioalkyl, polyalkoxyalkyl and cycloalkyl which can be interrupted by hetero atoms, each of which radicals is optionally substituted by halogen, or represents optionally substituted phenyl, optionally substituted phenylalkyl, substituted hetaryl, substituted phenoxyalkyl and substituted hetaryloxyalkyl, and

R² represents alkyl, alkenyl, alkoxyalkyl, polyalkoxyalkyl and optionally substituted phenyl or cycloalkyl, each of which radicals is optionally substituted by halogen,

A represents alkyl, alkenyl, alkinyl, alkoxyalkyl, polyalkoxyalkyl, alkylthioalkyl, or cycloalkyl which is optionally interrupted by hetero atoms, each of which radicals is optionally substituted by halogen, or represents arylalkyl which is optionally substituted by halogen, alkyl, halogenoalkyl, alkoxy or nitro,

B and C* independently of one another represent hydrogen, alkyl or alkoxyalkyl,

and the enantiomerically pure forms of compounds of the formula (I).

The following sub-groups may be as defined below:

(Ia): Compounds of the formula (I) where R is hydrogen,

(Ib): Compounds of the formula (I) where R is COR¹,

(Ic): Compounds of the formula (I) where R is COOR².

Furthermore, it has been found that 3-arylpyrrolidine-2,4-diones or the enols thereof, of the formula (Ia) ##STR3## in which A, B, C*, X, Y, Z and n have the abovementioned meanings, are obtained when

(A)

N-acylamino acid esters of the formula (II) ##STR4## in which A, B, C*, X, Y, Z and n have the abovementioned meanings and R³ represents alkyl, are subjected to intramolecular condensation in the presence of a diluent and in the presence of a base.

(B)

Moreover, it has been found that compounds of the formula (Ib) ##STR5## in which A, B, C*, X, Y, Z, R¹ and n have the abovementioned meanings, are obtained when compounds of the formula (Ia) ##STR6## in which A, B, C*, X, Y, Z and n have the abovementioned meanings, are reacted

a) with acid halides of the general formula (III) ##STR7## in which R¹ has the abovementioned meaning and Hal represents halogen, in particular chlorine and bromine, if appropriate in the presence of a diluent and if appropriate in the presence of an acid-binding agent, or

b) with carboxylic anhydrides of the general formula (IV)

    R.sup.1 -CO-O-CO-R.sup.1                                   (IV)

in which R¹ has the abovementioned meaning, if appropriate in the presence of a diluent and if appropriate in the presence of an acid-binding agent.

(C)

Furthermore, it has been found that compounds of the formula (Ic) ##STR8## in which A, B, C*, X, Y, Z, R² and n have the abovementioned meanings, are obtained when compounds of the formula (Ia) ##STR9## in which A, B, C*, X, Y, Z and n have the abovementioned meanings, are reacted with chloroformic acid esters of the general formula (V)

    R.sup.2 -O-CO-Cl                                           (V)

in which R² has the abovementioned meaning, if appropriate in the presence of a diluent and if appropriate in the presence of an acid-binding agent.

Surprisingly, it has been found that the new 3-arylpyrrolidine-2,4-dione derivatives of the formula (I) are distinguished by outstanding insecticidal, acaricidal, herbicidal and antimycotic actions.

Preferred 3-aryl-pyrrolidine-2,4-dione derivatives of the formula (I) are those in which

X represents C₁ -C₆ -alkyl, halogen and C₁ -C₆ -alkoxy,

Y represents hydrogen, C₁ -C₆ -alkyl, halogen, C₁ -C₆ -alkoxy, and C₁ -C₃ -halogenoalkyl,

Z represents C₁ -C₆ -alkyl, halogen and C₁ -C₆ -alkoxy,

n represents a number from 0-3,

R represents hydrogen (Ia) or represents the groups of the formula

    --CO--R.sup.1 (Ib) or --CO--O--R.sup.2 (Ic)

in which

R¹ represents C₁ -C₂₀ -alkyl, C₂ -C₂₀ -alkenyl, C₁ -C₈ -alkoxy-C₂ -C₈ -alkyl, C₁ -C₈ -alkylthio-C₂ -C₈ -alkyl, C₁ -C₈ -polyalkoxy-C₂ -C₈ -alkyl and cycloalkyl which has 3-8 ring atoms and which can be interrupted by oxygen and/or sulphur, each of which radicals is optionally substituted by halogen, or represents phenyl which is optionally substituted by halogen, nitro, C₁ -C₆ -alkyl, C₁ -C₆ -alkoxy, C₁ -C₆ -halogenoalkyl or C₁ -C₆ -halogenoalkoxy; or represents phenyl-C₁ -C₆ -alkyl which is optionally substituted by halogen, C₁ -C₆ -alkyl, C₁ -C₆ -alkoxy, C₁ -C₆ -halogenoalkyl or C₁ -C₆ -halogenoalkoxy, or represents hetaryl which is optionally substituted by halogen and C₁ -C₆ -alkyl, or represents phenoxy-C₁ -C₆ -alkyl which is optionally substituted by halogen and C₁ -C₆ -alkyl, or represents hetaryloxy-C₁ -C₆ -alkyl which is optionally substituted by halogen, amino and C₁ -C₆ -alkyl,

R² represents C₁ -C₂₀ -alkyl, C₂ -C₂₀ -alkenyl, C₁ -C₈ -alkoxy-C₂ -C₈ -alkyl and C₁ -C₈ -polyalkoxy-C₂ -C₈ -alkyl, each of which radicals is optionally substituted by halogen, or represents phenyl or cycloalkyl which has 3-8 ring atoms, each of which radicals is optionally substituted by halogen nitro, C₁ -C₆ -alkyl, C₁ -C₆ -alkoxy or C₁ -C₆ -halogenoalkyl,

A represents straight-chain or branched C₁ -C₁₂ -alkyl, C₃ -C₈ -alkenyl, C₃ -C₈ -alkinyl, C₁ -C₁₀ -alkoxy-C₂ -C₈ -alkyl, C₁ -C₈ -polyalkoxy-C₂ -C₈ -alkyl, C₁ -C₁₀ -alkylthio-C₂ -C₈ -alkyl or cycloalkyl which has 3-8 ring atoms and which can be interrupted by oxygen and/or sulphur, each of which radicals is optionally substituted by halogen, or represents aryl-C₁ -C₆ -alkyl which is optionally substituted by halogen, C₁ -C₆ -alkyl-C₁ -C₆ -haloalkyl, C₁ -C₆ -alkoxy or nitro,

B and C* independently of one another represent hydrogen, straight-chain or branched C₁ -C₁₂ -alkyl or C₁ -C₈ -alkoxyalkyl,

and the enantiomerically pure forms of compounds of the formula (I).

Particularly preferred compounds of the formula (I) are those in which

X represents C₁ -C₄ -alkyl, halogen and C₁ -C₄ -alkoxy,

Y represents hydrogen, C₁ -C₆ -alkyl, halogen, C₁ -C₄ -alkoxy and C₁ -C₂ -halogenoalkyl,

Z represents C₁ -C₄ -alkyl, halogen and C₁ -C₄ -alkoxy,

n represents a number from 0-3,

R represents hydrogen (Ia) or represents the groups of the formula

    --CO--R.sup.1 (Ib) or --CO--O--R.sup.2 (Ic)

in which

R¹ represents C₁ -C₁₆ -alkyl, C₂ -C₁₆ -alkenyl, C₁ -C₆ -alkoxy-C₂ -C₆ -alkyl, C₁ -C₆ -alkylthio-C₂ -C₆ -alkyl, C₁ -C₆ -polyalkoxy-C₂ -C₆ -alkyl and cycloalkyl which has 3-7 ring atoms and which can be interrupted by 1-2 oxygen and/or sulphur atoms, each of which radicals is optionally substituted by halogen, or represents phenyl which is optionally substituted by halogen, nitro, C₁ -C₄ -alkyl, C₁ -C₄ -alkoxy, C₁ -C₃ -halogenoalkyl or C₁ -C₃ -halogenoalkoxy, or represents phenyl-C₁ -C₄ -alkyl which is optionally substituted by halogen, C₁ -C₄ -alkyl, C₁ -C₄ -alkoxy, C₁ -C₃ -halogenoalkyl or C₁ -C₃ -halogenoalkoxy, or represents hetaryl which is optionally substituted by halogen and C₁ -C₆ -alkyl, or represents phenoxy-C₁ -C₅ -alkyl which is optionally substituted by halogen and C₁ -C₄ -alkyl, or represents hetaryloxy-C₁ -C₅ -alkyl which is optionally substituted by halogen, amino and C₁ -C₄ -alkyl,

R² represents C₁ -C₁₆ -alkyl, C₂ -C₁₆ -alkenyl, C₁ -C₁₆ -alkoxy-C₂ -C₆ -alkyl and C₁ -C₆ -polyalkoxy-C₂ -C₆ -alkyl, each of which radicals is optionally substituted by halogen, or represents phenyl or cycloalkyl which has 3-7 ring atoms each of which radicals is optionally substituted by halogen, nitro, C₁ -C₄ -alkyl, C₁ -C₃ -alkoxy or C₁ -C₃ -halogenoalkyl,

A represents straight-chain or branched C₁ -C₁₀ -alkyl, C₃ -C₆ -alkenyl, C₃ -C₆ -alkinyl, C₁ -C₈ -alkoxy-C₂ -C₆ -alkyl, C₁ -C₆ -polyalkoxy-C₂ -C₆ -alkyl, C₁ -C₈ -alkylthio-C₂ -C₆ -alkyl or cycloalkyl which has 3-7 ring atoms and which can be interrupted by 1-2 oxygen and/or sulphur atoms, each of which radicals is optionally substituted by halogen, or represents aryl-C₁ -C₄ -alkyl which is optionally substituted by halogen, C₁ -C₄ -alkyl, C₁ -C₄ -haloalkyl-C₁ -C₄ -alkoxy or nitro,

B and C* independently of one another represent hydrogen, straight-chain or branched C₁ -C₁₀ -alkyl and C₁ -C₆ -alkoxyalkyl,

and the enantiomerically pure forms of compounds of the formula (I).

Very particularly preferred compounds of the formula (I) are those in which

X represents methyl, ethyl, propyl, i-propyl, fluorine, chlorine, bromine, methoxy and ethoxy,

Y represents hydrogen, methyl, ethyl, propyl, i-propyl, butyl, i-butyl, tert.-butyl, fluorine, chlorine, bromine, methoxy, ethoxy and trifluoromethyl,

Z represents methyl, ethyl, i-propyl, butyl, i-butyl, tert.-butyl, fluorine, chlorine, bromine, methoxy and ethoxy,

n represents a number from 0-3,

R represents hydrogen (Ia) or represents the groups of the formula

    --CO--R.sup.1 (Ib) or --CO--O--R.sup.2 (Ic)

in which

R¹ represents C₁ -C₁₄ -alkyl, C₂ -C₁₄ -alkenyl, C₁ -C₄ -alkoxy-C₂ -C₆ -alkyl, C₁ -C₄ -alkylthio-C₂ -C₆ -alkyl, C₁ -C₄ -polyalkoxyl-C₂ -C₄ -alkyl and cycloalkyl which has 3-6 ring atoms and which can be interrupted by 1-2 oxygen and/or sulphur atoms, each of which radicals is optionally substituted by fluorine or chlorine, or represents phenyl which is optionally substituted by fluorine, chlorine, bromine, methyl, ethyl, propyl, i-propyl, methoxy, ethoxy, trifluoromethyl, trifluoromethoxy or nitro, or represents phenyl-C₁ -C₃ -alkyl which is optionally substituted by fluorine, chlorine, bromine, methyl, ethyl, propyl, i-propyl, methoxy, ethoxy, trifluoromethyl or trifluoromethoxy, or represents pyridyl, pyrimidyl, thiazolyl and pyrazolyl, each of which radicals is optionally substituted by fluorine, chlorine, bromine, methyl or ethyl, or represents phenoxy-C₁ -C₄ -alkyl which is optionally substituted by fluorine, chlorine, methyl or ethyl, or represents pyridyloxy-C₁ -C₄ -alkyl, pyrimidyloxy-C₁ -C₄ -alkyl and thiazolyloxy-C₁ -C₄ -alkyl, each of which radicals is optionally substituted by fluorine, chlorine, amino, methyl or ethyl,

R² represents C₁ -C₁₄ -alkyl, C₂ -C₁₄ -alkenyl, C₁ -C₄ -alkoxy-C₂ -C₆ -alkyl and C₁ -C₄ -polyalkoxy-C₂ -C₆ -alkyl, each of which radicals is optionally substituted by fluorine or chlorine, or represents phenyl or cycloalkyl which has 3-6 ring atoms, each of which radicals is optionally substituted by fluorine, chlorine, nitro, methyl, ethyl, propyl, i-propyl, methoxy, ethoxy or trifluoromethyl,

A represents straight-chain or branched C₁ -C₄ -alkyl, C₃ -C₄ -alkenyl, C₃ -C₄ -alkinyl, C₁ -C₆ -alkoxy-C₂ -C₄ -alkyl, C₁ -C₄ -polyalkoxy-C₂ -C₄ -alkyl, C₁ -C₆ -alkylthio-C₂ -C₄ -alkyl and cycloalkyl which has 3-6 ring atoms and which can be interrupted by 1-2 oxygen and/or sulphur atoms, each of which radicals is optionally substituted by halogen, or represents aryl-C₁ -C₃ -alkyl which is optionally substituted by fluorine, chlorine, bromine, methyl, ethyl, propyl, isopropyl, methoxy, ethoxy, trifluoromethyl or nitro,

B and C* independently of one another represent hydrogen, straight-chain or branched C₁ -C₈ -alkyl and C₁ -C₄ -alkoxyalkyl,

and the enantiomerically pure forms of compounds of the formula I.

If, in accordance with process (A), N-2,6-dichlorophenyl-acetyl-N-methyl-alanine ethyl ester is used, the procedure of the process according to the invention can be represented by the following equation: ##STR10##

If, in accordance with process (B) (variant a), 3-(2,4,6-trimethylphenyl)-1-isopropyl-pyrrolidin-2,4-dione and pivaloyl chloride are used as the starting substances, the course of the process according to the invention can be represented by the following equation: ##STR11##

If, in accordance with process (B) (variant b), 3-(2,4,6-trimethylphenyl)-1-cyclopentyl-pyrrolidine-2,4-dione and acetic anhydride are used, the course of the process according to the invention can be represented by the following equation. ##STR12##

If, in accordance with process C, 3-(2,4-6-trimethylphenyl)-1-methoxyethyl-5-methyl-pyrrolidine-2,4-dione and ethoxyethyl chloroformate are used, the course of the process according to the invention can be represented by the following equation. ##STR13##

The compounds of the formula (II) ##STR14## in which A, B, C*, X, Y, Z, n and R³ have the abovementioned meanings and which are required as starting substances in the above process (A) are known in some cases, or they can be prepared in a simple manner by methods which are known in principle. Thus, for example, acylamino acid esters of the formula (II) are obtained when

a) amino acid esters of the formula (VI) ##STR15## in which R⁴ represents hydrogen (VIa) and alkyl (VIb) and A, B and C* have the abovementioned meanings, are acylated with phenylacetic acid halides of the formula (VII) ##STR16## in which X, Y, Z and n have the abovementioned meanings, and Hal represents chlorine or bromine (Chem. Reviews 52 237-416 (1953));

or when acylamino acids of the formula (IIa) ##STR17## in which A, B, C*, X, Y, Z and n have the abovementioned meanings and R⁴ represents hydrogen, are esterified (Chem. Ind. (London) 1568 (1968).

Exemplary are the following compounds of the formula (II)

1. N-isopropyl-N-(2,4-dichlorophenyl-acetyl)-glycin-ethylester

2. N-isopropyl-N-(2,6-dichlorophenyl-acetyl)-glycin-ethylester

3. N-(2,6-dichlorophenyl-acetyl)-sarkosine-methylester

4. N-isopropyl-N-(2,6-dichlorophenyl-acetyl)-alanin-ethylester

5. N-methoxyethyl-N-(2,6-dichlorophenyl-acetyl)-glycin-ethylester

6. N-methoxyethyl-N-(2,6-dichlorophenyl-acetyl)-alanin-ethylester

7. N-tert-butyl-N-(2,6-dichlorophenyl-acetyl)-glycin-ethylester

8. N-methyl-N-(2,6-dichlorophenyl-acetyl)-alanin-ethylester

9. N-2-(2,4,4-trimethyl-pentyl)-N-(2,6-dichlorophenyl-acetyl)-glycin-ethylester

10. N-(2,4,6,-trimethylphenyl-acetyl)-sarkosine-ethylester

11. N-ethyl-N-(2,4,6-trimethylphenyl-acetyl)-glycin-methylester

12. N-isopropyl-N-(2,4,6-trimethylphenyl-acetyl)-glycin-ethylester

13. N-tert.-butyl-N-(2,4,6-trimethylphenyl-acetyl)-glycin-ethylester

14. N-iso-butyl-N-(2,4,6-trimethylphenyl-acetyl)-glycin-ethylester

15. N-sec-butyl-N-(2,4,6-trimethylphenyl-acetyl)-glycin-ethylester

16. N-neo-pentyl-N-(2,4,6-trimethylphenyl-acetyl)-glycin-ethylester

17. N-2-(2,3-dimethyl-butyl)-N-(2,4,6-trimethylphenyl-acetyl)-glycin-ethylester

18. N-2-(2,2,3-trimethyl-butyl)-N-(2,4,6-trimethylphenyl-acetyl)-glycin-ethylester

19. N-cyclopropyl-N-(2,4,6-trimethylphenyl-acetyl)-glycin-ethylester

20. N-cyclopentyl-N-(2,4,6-trimethylphenyl-acetyl)-glycin-ethylester

21. N-cyclohexyl-N-(2,4,6-trimethylphenyl-acetyl)-glycin-ethylester

22. N-alkyl-N-(2,4,6-trimethylphenyl-acetyl)-glycin-ethylester

23. N-benzyl-N-(2,4,6-trimethylphenyl-acetyl)-glycin-ethylester

24. N-2-(2,4,4-trimethyl-pentyl)-N-(2,4,6-trimethyl-phenyl-acetyl)-glycin-ethylester

25. N-methoxyethyl-N-(2,4,6-trimethylphenyl-acetyl)-glycin-ethylester

26. N-methoxypropyl-N-(2,4,6-trimethylphenyl-acetyl)-glycin-ethylester

27. N-methoxy-2-methyl-propyl-N-(2,4,6-trimethylphenyl-acetyl)-glycin-ethylester

28. N-2-(ethoxy-butyl)-N-(2,4,6-trimethylphenyl-acetyl)-glycin-ethylester

29. N-2-(methoxy-propyl)-N-(2,4,6-trimethylphenyl-acetyl) -glycin-ethylester

30. N-ethyl-mercaptoethyl-N-(2,4,6-trimethylphenyl-acetyl)-glycin-ethylester

31. N-methyl-N-(2,4,6-trimethylphenyl-acetyl)-alanin-ethylester

32. N-ethyl-N-(2,4,6-trimethylEpP098Ahenyl-acetyl)-alanin-ethylester

33. N-isopropyl-N-(2,4,6-trimethylphenyl-acetyl)-alanin-ethylester

34. N-isobutyl-N-(2,4,6-trimethylphenyl-acetyl)-alanin-ethylester

35. N-sec-butyl-N-(2,4,6-trimethylphenyl-acetyl)-alanin-ethylester

36. N-cyclopropyl-N-(2,4,6-trimethylphenyl-acetyl)-alanin-ethylester

37. N-cyclopropyl-N-(2,4,6-trimethylphenyl-acetyl)-alanin-ethylester

38. N-cyclohexyl-N-(2,4,6-trimethylphenyl-acetyl)-alanin-ethylester

39. N-methoxyethyl-N-(2,4,6-trimethylphenyl-acetyl)-alanin-ethylester

40. N-methoxypropyl-N-(2,4,6-trimethylphenyl-acetyl)-alanin-ethylester

41. N-methyl-N-(2,4,6-trimethylphenyl-acetyl)-2-amino-butyric acid-ethylester

42. N-ethyl-N-(2,4,6-trimethylphenyl-acetyl)-2-amino-butyric acid-ethylester

43. N-methyl-N-(2,4,6-trimethylphenyl-acetyl)-2-amino-valerian acid-ethylester

44. N-methyl-N-(2,4,6-trimethylphenyl-acetyl)-2-amino-iso-valerian acid-ethylester

45. N-ethyl-N-(2,4,6-trimethylphenyl-acetyl)-2-amino-valerian acid-ethylester

46. N-ethyl-N-(2,4,6-trimethylphenyl-acetyl)-2-amino-iso-valerian acid-ethylester

47. N-methyl-N-(2,4,6-trimethylphenyl-acetyl)-2-methyl-alanin-ethylester

48. N-ethyl-N-(2,4,6-trimethylphenyl-acetyl)-2-methyl-alanin-ethylester

49. N-isopropyl-N-(2,4,6-trimethylphenyl-acetyl)-2-methylalanin-ethylester

Compounds of the formula (IIa) can be obtained, for example, from the phenylacetic acid halides of the formula (VII) and amino acids of the formula (VIa) by the method of Schotten-Baumann (Organikum [Laboratory Practical Organic Chemistry]9th Edition 446 (1970) VEB Deutscher Verlag der Wissenschaften, Berlin).

Compounds of the formula VI in which A, B, C and R⁴ have the abovementioned meaning can be obtained by processes which are known from the literature, from a-halogenocarboxylic acids or esters and amines (Advanced Organic Chemistry, J. March p. 377, McGraw-Hill Inc. 1977).

Process (A) is characterized in that compounds of the formula (II) in which A, B, C, X, Y, Z, m, n and R³ have the abovementioned meanings are subjected to intramolecular condensation in the presence of bases.

Diluents which can be employed in process (A) according to the invention are all customary inert organic solvents. Hydrocarbons, such as toluene and xylene, furthermore ethers, such as dibutyl ether, tetrahydrofuran, dioxane, glycol dimethyl ether and diglycol dimethyl ether, and also polar solvents, such as dimethyl sulphoxide, sulpholane, dimethylformamide and N-methyl-pyrrolidone, can preferably be used.

Deprotonating agents which can be employed when carrying out process (A) according to the invention are all customary proton acceptors. The oxides, hydroxides and carbonates of alkali metals and alkaline earth metals, such as sodium hydroxide, potassium hydroxide, magnesium oxide, calcium oxide, sodium carbonate, potassium carbonate and calcium carbonate, which can also be employed in the presence of phase transfer catalysts, such as, for example, triethylbenzylammonium chloride, tetrabutylammonium bromide, Adogen 464 (methyltrialkyl (C₈ -C₁₀)ammonium chloride) or TDA 1 (tris-(methoxyethoxylethyl)-amine), can preferably be used. Furthermore, amides and hydrides of alkali metals and alkaline earth metals, such as sodium amide, sodium hydride and calcium hydride, and additionally also alkali metal alkoxides, such as sodium methoxide, sodium methoxide and potassium tert.-butoxide, can also be employed.

When carrying out process (A) according to the invention, the reaction temperatures can be varied within a substantial range. In general, the process is carried out at temperatures between 0° C. and 250° C., preferably between 50° C. and 150° C.

Process (A) according to the invention is generally carried out under atmospheric pressure.

When carrying out process (A) according to the invention, the reactants of the formulae (II) and the deprotonating bases are generally employed in approximately equimolar amounts. However, it is also possible to use one or the other components in a substantial excess (up to 3 moles).

Process (Ba) is characterized in that compounds of the formula (Ia) are reacted with carboxylic acid halides of the formula (III).

When the acid halides are used, the diluents which can be employed in process (Ba) according to the invention are all solvents which are inert towards these compounds. Hydrocarbons, such as benzine, benzene, toluene, xylene and tetralin, furthermore halogenohydrocarbons, such as methylene chloride, chloroform, carbon tetrachloride, chlorobenzene and o-dichlorobenzene, and additionally ketones, such as acetone and methyl isopropyl ketone, furthermore ethers, such as diethyl ether, tetrahydrofuran and dioxane, moreover carboxylic acid esters, such as ethyl acetate, and also strongly polar solvents, such as dimethyl sulphoxide and sulpholane, can preferably be used. If the stability of the acid halide towards hydrolysis permits, the reaction can also be carried out in the presence of water.

If the corresponding carboxylic acid halides are used, suitable acid-binding agents in the reaction of process (Ba) according to the invention are all customary acid acceptors. Tertiary amines, such as triethylamine, pyridine, diazabicyclooctane (DABCO), diazabicycloundecene (DBU), diazabicyclononbene (DBN), Hunig base and N,N-dimethyl-aniline, furthermore, alkaline earth metal oxides, such as magnesium oxide and calcium oxide, additionally alkali metal carbonates and alkaline earth metal carbonates, such as sodium carbonate, potassium carbonate and calcium carbonate, can preferably be used.

In process (Ba) according to the invention, the reaction temperatures can be varied within a substantial range, also when carboxylic acid halides are used. In general, the process is carried out at temperatures between -20° C. and +150° C., preferably between 0° C. and 100° C.

When carrying out process (Ba) according to the invention, the starting substances of the formula (Ia) and the carboxylic acid halide of the formula (III) are generally used in approximately equivalent amounts. However, it is also possible to employ the carboxylic anhydride in a substantial excess (up to 5 moles). Working up is carried out by customary methods.

Process (Bb) is characterized in that compounds of the formula (Ia) are reacted with carboxylic acid anhydrides of the formula (IV).

If, in process (Bb) according to the invention, carboxylic anhydrides are used as the reactant of the formula (IV), the diluents which can preferably be used are those diluents which are also preferably suitable when acid halides are used. Besides, a carboxylic acid anhydride, employed in excess, can also simultaneously act as the diluent.

When carrying out process (Bb) according to the invention, the reaction temperatures can be varied within a substantial range, also when carboxylic anhydrides are used. In general, the process is carried out at temperatures between -20° C. and +150° C., preferably between 0° C. and 100° C.

When the process according to the invention is carried out, the starting substances of the formula (Ia) and the carboxylic anhydride of the formula (IV) are generally used in approximately equivalent amounts. However, it is also possible to employ the carboxylic anhydride in a substantial excess (up to 5 moles). Working up is carried out by customary methods.

In general, a procedure is followed in which the diluent and any carboxylic anhydride which is present in excess as well as the carboxylic acid which forms are removed by distillation or by washing with an organic solvent or with water.

Process (C) is characterized in that compounds of the formula (Ia) are reacted with chloroformic acid esters of the formula (V).

If the corresponding chloroformic acit esters are used, suitable acid-binding agents in the reaction in process (C) according to the invention are all customary acid acceptors. Tertiary amines, such as triethylamine, pyridine, DABCO, DBC, DBA, Hunig base and N,N-dimethylaniline, furthermore alkaline earth metal oxides, such as magnesium oxide and calcium oxide, and additionally alkali metal carbonates and alkaline earth metal carbonates, such as sodium carbonate, potassium carbonate and calcium carbonate, can preferably be used.

When the chloroformic acid esters are used, the diluents which can be employed in process (C) according to the invention are all solvents which are inert towards these compounds. Hydrocarbons, such as benzine, benzene, toluene, xylene and tetralin, furthermore halogenohydrocarbons, such as methylene chloride, chloroform, carbon tetrachloride, chlorobenzene and o-dichlorobenzene, additionally ketones, such as acetone and methyl isopropyl ketone, furthermore ethers, such as diethyl ether, tetrahydrofuran and dioxane, moreover carboxylic acid esters, such as ethyl acetate, and also strongly polar solvents, such as dimethyl sulphoxide and sulpholane, can preferably be used.

When the chloroformic acid esters are used as carboxylic acid derivatives of the formula (V), the reaction temperatures can be varied within a substantial range when process (C) is carried out. If the process is carried out in the presence of a diluent and of an acid-binding agent, the reaction temperatures are generally between -20° C. and +100° C., preferably between 0° C. and 50° C.

Process (C) according to the invention is generally carried out under atmospheric pressure.

When process (C) according to the invention is carried out, the starting substances of the formula (Ia) and the corresponding chloroformic acid ester of the formula (V) are generally used in approximately equivalent amounts. However, it is also possible to employ one or the other component in a substantial excess (up to 2 moles). Working up is then carried out by customary methods. In general, a procedure is followed in which the salts which have precipitated are removed and the reaction mixture which remains is concentrated by stripping off the diluent.

EXAMPLE 1 ##STR18##

3.9 g (0.13 mol) of sodium hydride (80% strength) are initially introduced into 70 ml of absolute toluene. After 36.2 g (0.107 mol) of N-2,6-dichlorophenylacetyl-N-isopropyl-glycine ethyl ester in 160 ml of absolute toluene have been added dropwise, the mixture is refluxed for 6 hours. 20 ml of ethanol are added dropwise while cooling in an ice bath, the batch is evaporated in vacuo on a rotary evaporator, the residue is dissolved in 1 N NaOH, and 3-(2,6-dichlorophenyl)-1-isopropyl-pyrrolidine-2,4-dione is precipitated at 0°-20° C. using concentrated hydrochloric acid. For purification, the product is boiled in chloroform, n-hexane is subsequently added, and the colorless product which has precipitated is filtered off with suction.

Yield: 25.42 g (83 % of theory) m.p. >230° C.

EXAMPLE 2 ##STR19##

3.42 g (15 mmol) of 3-(2,4,6-trimethylphenyl)-1 -methyl-pyrrolidine-2,4-dione are suspended in 50 ml of absolute tetrahydrofuran (THF), and 1.22 ml (15 mmol) of absolute pyridine and 2.54 ml (15 mmol) of ethyl-diisopropylamine are added. To this, 1.88 ml (15 mmol) of pivaloyl chloride dissolved in 5 ml of absolute THF are added dropwise at 0°-10° C., and stirring is continued for 30 minutes. The precikpitate is filtered off, the solution is evaporated in vacuo on a rotary evaporator, and the residue is chromatographed on silica gel using cyclohexane/ethyl acetate 1:1.

Crystallization from ether/n-hexane gives 3.8 g (80.4% of theory) of 4-(pivaloyloxy)-3-(2,4,6-trimethylphenyl)-1-methyl-3-pyrrolidine-2-one of melting point 75° C.

EXAMPLE 3 ##STR20##

5.18 g (20 mmol) of 3-(2,4,6-trimethyl-phenyl)-1-isopropyl-pyrrolidine-2,4-dione are suspended in 70 ml of tert.butyl-methyl ether (MTB-ether). After addition of 1.63 ml (20 mmol) of absolute pyridine and 3.4 ml (20 mmol) of ethyl-diisopropylamine 2.45 g (20 mmol) chloroformic acid-iso-propylester dissolved in 5 ml of MTB-ether are added dropwise at 0° to 10° C. and stirring is continued for 30 minutes. The precipitate is filtered off, the solution is evaporated in vacuo on a rotary evaporator and the residue is chromatographed on silica gel using cyclohexane/ethylacetate 1:1. Crystallization from n-hexane gives 4.67 g (67.6% of theory) of 4-isopropoxy-carbonyloxy-3-(2,4,6-trimethylphenyl)-1-isopropyl-3-pyrrolin-2-one of melting point 81° C. The 3-aryl-pyrrolidine-2,4-dione derivatives of the formula (Ia)-(Ic), which are listed in Tables 1-3 below by way of their formulae, are obtained analogously to the Preparation Examples and following the general preparation instructions.

                                      TABLE 1                                      __________________________________________________________________________      ##STR21##                                    (Ia)                             Ex. No.                                                                             X  Y  Z.sub.n                                                                            A                 B      C*  mp °C.                      __________________________________________________________________________      4   Cl Cl H   (CH.sub.3).sub.2 CH                                                                              H      H   198                                 5   Cl H  6-Cl                                                                               CH.sub.3          H      H   230                                 6   Cl H  6-Cl                                                                               CH.sub.3          CH.sub.3                                                                              H   221                                 7   Cl H  6-Cl                                                                               (CH.sub.3).sub.2 CH                                                                              CH.sub.3                                                                              CH.sub.3                                                                           180                                 8   Cl H  6-Cl                                                                               (CH.sub.3).sub.3 C                                                                               H      H   >230                                9   Cl H  6-Cl                                                                               (CH.sub.3).sub.3 CCH.sub.2C(CH.sub.3).sub.2                                                      H      H   >235                               10   Cl H  6-Cl                                                                               (CH.sub.3 O(CH.sub.2).sub.2                                                                      H      H   >230                               11   Cl H  6-Cl                                                                               CH.sub.3O(CH.sub.2).sub. 2                                                                       H      H   128                                12   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3          H      H   >230                               13   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3          CH.sub.3                                                                              H   >230                               14   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3          C.sub.2 H.sub.5                                                                       H   210                                15   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3          C.sub.3 H.sub.7                                                                       H                                      16   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3          (CH.sub.3).sub.2 CH                                                                   H                                      17   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3          CH.sub.3                                                                              CH.sub.3                               18   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5   H      H   >230                               19   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5   CH.sub.3                                                                              H   227                                20   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5   C.sub.2 H.sub.5                                                                       H   184                                21   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5   C.sub.3 H.sub.7                                                                       H                                      22   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5   (CH.sub.3).sub.2 CH                                                                   H                                      23   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5   CH.sub.3                                                                              CH.sub.3                               24   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7   H      H                                      25   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7   CH.sub.3                                                                              H                                      26   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7   C.sub.2 H.sub.5                                                                       H                                      27   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7   C.sub.3 H.sub.7                                                                       H                                      28   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7   (CH.sub.3).sub.2 CH                                                                   H                                      29   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7   CH.sub.3                                                                              CH.sub.3                               30   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                              H      H   >220                               31   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                              CH.sub.3                                                                              H   228                                32   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                              C.sub.2 H.sub.5                                                                       H                                      33   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                              C.sub.3 H.sub.7                                                                       H                                      34   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                              (CH.sub.3).sub.2 CH                                                                   H                                      35   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3 ).sub.2 CH                                                                             CH.sub.3                                                                              CH.sub.3                               36   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.4 H.sub.9   H      H                                      37   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.4 H.sub.9   CH.sub.3                                                                              H                                      38   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CHCH.sub.2                                                                      H      H   209                                39   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CHCH.sub.2                                                                      CH.sub.3                                                                              H   189                                40   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR22##        H      H   262                                41   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR23##        CH.sub.3                                                                              H   205                                42   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.3 C                                                                               H      H   >230                               43   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.3 CCH.sub.2                                                                       H      H   >230                               44   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CHCH(CH.sub.3)                                                                  H      H   >230                               45   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.3 CCH(CH.sub.3 )                                                                  H      H   >230                               46   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.3 CCH.sub.2C(CH.sub.3).sub.2                                                      H      H   >230                               47   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.2CHCH.sub.2                                                                               H      H   212                                48   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.2CHCH.sub.2                                                                               CH.sub.3                                                                              H                                      49   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR24##        H      H   >230                               50   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR25##        CH.sub.3                                                                              H   >230                               51   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR26##        C.sub.2 H.sub.5                                                                       H                                      52   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR27##        C.sub.3 H.sub.7                                                                       H                                      53   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR28##        (CH.sub.3).sub.2 CH                                                                   H                                      54   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR29##        CH.sub.3                                                                              CH.sub.3                               55   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR30##        H      H   >230                               56   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR31##        CH.sub.3                                                                              H   223                                57   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR32##        C.sub.2 H.sub.5                                                                       H                                      58   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR33##        C.sub.3 H.sub.7                                                                       H                                      59   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR34##        (CH.sub.3).sub.2 CH                                                                   H                                      60   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR35##        CH.sub.3                                                                              CH.sub.3                               61   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR36##        H      H   >230                               62   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR37##        CH.sub.3                                                                              H   >230                               63   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR38##        C.sub.2 H.sub.5                                                                       H                                      64   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR39##        C.sub.3 H.sub.7                                                                       H                                      65   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR40##        (CH.sub.3 ).sub.2 CH                                                                  H                                      66   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR41##        CH.sub.3                                                                              CH.sub.3                               67   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR42##        H      H   >230                               68   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR43##        CH.sub.3                                                                              H                                      69   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3O(CH.sub.2).sub.2                                                                        H      H   179                                70   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3O(CH.sub.2).sub.2                                                                        CH.sub.3                                                                              H   165                                71   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3OCH.sub.2CH(CH.sub.3)                                                                    H      H   220                                72   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3OCH.sub.2CH(CH.sub.3)                                                                    CH.sub.3                                                                              H                                      73   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3O(CH.sub.2).sub.3                                                                        H      H   190                                74   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3O(CH.sub.2).sub.3                                                                        CH.sub.3                                                                              H   175                                75   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5O(CH.sub.2).sub.2CH(CH.sub.3)                                                     H      H   220                                76   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5O(CH.sub.2).sub.2CH(CH.sub.3)                                                     CH.sub.3                                                                              H                                      77   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3OCH.sub.2CH(CH.sub.3)CH.sub.2                                                            H      H   156                                78   CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5S(CH.sub.2).sub.2                                                                 H      H   165                                __________________________________________________________________________

                                      TABLE 2                                      __________________________________________________________________________      ##STR44##                                             (Ib)                    Ex.                                                                            No.                                                                               X  Y  Z.sub.n                                                                            A                B      C*  R.sup.1      mp                       __________________________________________________________________________                                                           °C.                79                                                                               Cl Cl H   (CH.sub.3).sub.2)CH                                                                             H      H   CH.sub.3     128                       80                                                                               Cl H  6-Cl                                                                               CH.sub.3         CH.sub.3                                                                              H   CH.sub.3     125                       81                                                                               Cl H  6-Cl                                                                               CH.sub.3         CH.sub.3                                                                              H   (CH.sub.3).sub.2 CH                                                                         Ol                        82                                                                               Cl H  6-Cl                                                                               CH.sub.3         CH.sub.3                                                                              H   (CH.sub.3).sub.3 C                                                                          68                        83                                                                               Cl H  6-Cl                                                                               (CH.sub.3).sub.2 CH                                                                             H      H   CH.sub.3     113                       84                                                                               Cl H  6-Cl                                                                               (CH.sub. 3).sub.2 CH                                                                            H      H   (CH.sub.3).sub.2 CH                                                                         105                       85                                                                               Cl H  6-Cl                                                                               (CH.sub.3).sub.2 CH                                                                             H      H   (CH.sub.3).sub.3 C                                                                          122                       86                                                                               Cl H  6-Cl                                                                               (CH.sub.3).sub.2 CH                                                                             H      H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2          112                       87                                                                               Cl H  6-Cl                                                                               (CH.sub.3).sub.3 C                                                                              H      H   CH.sub.3     113                       88                                                                               Cl H  6-Cl                                                                               (CH.sub.3).sub.3 C                                                                              H      H   (CH.sub.3).sub.2 CH                                                                         117                       89                                                                               Cl H  6-Cl                                                                               (CH.sub.3).sub.3 C                                                                              H      H   (CH.sub.3).sub.3 C                                                                          158                       90                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         H      H   CH.sub.3     Ol                        91                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         H      H   (CH.sub.3).sub.2 CH                                                                         Ol                        92                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         H      H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2          45                        93                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         CH.sub.3                                                                              H   CH.sub. 3    75                        94                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         CH.sub.3                                                                              H   (CH.sub.3).sub.2 CH                                                                         Ol                        95                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         CH.sub.3                                                                              H   (CH.sub.3).sub.3 C                                                                          Ol                        96                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         CH.sub.3                                                                              H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                    97                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         CH.sub.3                                                                              H   (CH.sub.3).sub.3 CCH.sub.2                                                                  oil                       98                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         CH.sub.3                                                                              H   CH.sub.3 OCH.sub.2C(CH.sub.3).sub                                              .2           oil                       99                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         CH.sub.3                                                                              H   ClCH.sub.2C(CH.sub.3).sub.2                                                                 oil                      100                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         CH.sub.3                                                                              H                                                                                   ##STR45##                            101                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         CH.sub.3                                                                              H   (CH.sub.3).sub.2 C CH                 102                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         CH.sub.3                                                                              H                                                                                   ##STR46##                            103                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         C.sub.2 H.sub.5                                                                       H   CH.sub.3                              104                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.2 CH                   105                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.3 C                    106                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   107                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.3 CCH.sub.2            108                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         C.sub.2 H.sub.5                                                                       H   CH.sub.3 OCH.sub.2C(CH.sub.3).sub                                              .2                                    109                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         C.sub.2 H.sub.5                                                                       H   ClCH.sub.2C(CH.sub.3).sub.2           110                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         C.sub.2 H.sub.5                                                                       H                                                                                   ##STR47##                            111                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.2 CCH                  112                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         C.sub.2 H.sub.5                                                                       H                                                                                   ##STR48##                            113                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         C.sub.3 H.sub.7                                                                       H   CH.sub.3                              114                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         C.sub.3 H.sub.7                                                                       H   (CH.sub.3).sub.2 CH                   115                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         C.sub.3 H.sub.7                                                                       H   (CH.sub.3).sub.3 C                    116                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         C.sub.3 H.sub.7                                                                       H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   117                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         (CH.sub. 3).sub.2 CH                                                                  H   CH.sub.3                              118                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         (CH.sub.3).sub.2 CH                                                                   H   (CH.sub.3).sub.2 CH                   119                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         (CH.sub.3).sub.2 CH                                                                   H   (CH.sub.3).sub.3 C                    120                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         (CH.sub.3).sub.2 CH                                                                   H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   121                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         CH.sub.3                                                                              CH.sub.3                                                                           CH.sub.3                              122                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         CH.sub.3                                                                              CH.sub.3                                                                           (CH.sub.3).sub.2 CH                   123                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         CH.sub.3                                                                              CH.sub.3                                                                           (CH.sub.3).sub.3 C                    124                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3         CH.sub.3                                                                              CH.sub.3                                                                           (CH.sub.3).sub.2CHC(CH.sub.3).sub                                              .2                                    125                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  H      H   CH.sub.3     85                       126                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  H      H   (CH.sub.3).sub.2 CH                   127                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  H      H   (CH.sub.3).sub.3 C                                                                          99                       128                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  H      H   (CH.sub.3).sub.2CHC(CH.sub.3).sub                                              .2                                    129                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  H      H   (CH.sub.3).sub.3 CCH.sub.2            130                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  H      H   CH.sub.3 OCH.sub.2C(CH.sub.3).sub                                              .2                                    131                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  H      H   ClCH.sub.2C(CH.sub.3).sub.2           132                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  H      H                                                                                   ##STR49##                            133                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  H      H   (CH.sub.3).sub.2 CCH                  134                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  H      H                                                                                   ##STR50##                            135                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  CH.sub.3                                                                              H   CH.sub.3     oil                      136                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  CH.sub.3                                                                              H   (CH.sub.3).sub.2 CH                   137                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  CH.sub.3                                                                              H   (CH.sub.3).sub.3 C                                                                          oil                      138                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  CH.sub.3                                                                              H   (CH.sub.3).sub.2CHC(CH.sub.3).sub                                              .2                                    139                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  CH.sub.3                                                                              H   (CH.sub.3).sub.3 CCH.sub.2                                                                  oil                      140                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  CH.sub.3                                                                              H   CH.sub.3 OCH.sub.2C(CH.sub.3).sub                                              .2                                    141                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  CH.sub.3                                                                              H   ClCH.sub.2C(CH.sub.3).sub.2           142                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  CH.sub.3                                                                              H                                                                                   ##STR51##                            143                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  CH.sub.3                                                                              H   (CH.sub.3).sub.2 CCH                  144                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  CH.sub.3                                                                              H                                                                                   ##STR52##                            145                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  C.sub.2 H.sub.5                                                                       H   CH.sub.3                              146                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.2 CH                   147                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.3 C                    148                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.2CHC(CH.sub.3).sub                                              .2                                    149                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.3 CCH.sub.2            150                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  C.sub.2 H.sub.5                                                                       H   CH.sub.3 OCH.sub.2C(CH.sub.3).sub                                              .2                                    151                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  C.sub.2 H.sub.5                                                                       H   ClCH.sub.2C(CH.sub.3).sub.2           152                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  C.sub.2 H.sub.5                                                                       H                                                                                   ##STR53##                            153                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.2 CCH                  154                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  C.sub.2 H.sub.5                                                                       H                                                                                   ##STR54##                            155                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  C.sub.3 H.sub.7                                                                       H   CH.sub.3                              156                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  C.sub.3 H.sub.7                                                                       H   (CH.sub.3).sub.2 CH                   157                                                                               CH.sub.3                                                                          CH.sub. 3                                                                         6-CH.sub.3                                                                         C.sub.2 H.sub.5  C.sub.3 H.sub.7                                                                       H   (CH.sub.3).sub.3 C                    158                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  C.sub.3 H.sub.7                                                                       H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   159                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  (CH.sub.3).sub.2 CH                                                                   H   CH.sub.3                              160                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  (CH.sub.3).sub.2 CH                                                                   H   (CH.sub.3).sub.2 CH                   161                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  (CH.sub.3).sub.2 CH                                                                   H   (CH.sub.3).sub.3 C                    162                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  (CH.sub.3).sub.2 CH                                                                   H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   163                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  CH.sub.3                                                                              CH.sub.3                                                                           CH.sub.3                              164                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  CH.sub.3                                                                              CH.sub.3                                                                           (CH.sub.3).sub.2 CH                   165                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub. 3                                                                        C.sub.2 H.sub.5  CH.sub.3                                                                              CH.sub.3                                                                           (CH.sub.3).sub.3 C                    166                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5  CH.sub.3                                                                              CH.sub.3                                                                           (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   167                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  H      H   CH.sub.3                              168                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  H      H   (CH.sub.3).sub.2 CH                   169                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  H      H   (CH.sub.3).sub.3 C                    170                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  H      H   (CH.sub.3).sub.2CHC(CH.sub.3).sub                                              .2                                    171                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  H      H   (CH.sub.3).sub.3 CCH.sub.3            172                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  H      H   CH.sub.3 OCH.sub.2C(CH.sub.3).sub                                              .2                                    173                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  H      H   ClCH.sub.2C(CH.sub.3).sub.2           174                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub. 3                                                                        C.sub.3 H.sub.7  H      H                                                                                   ##STR55##                            175                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  H      H   (CH.sub.3).sub.2 CCH                  176                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  H      H                                                                                   ##STR56##                            177                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  CH.sub.3                                                                              H   CH.sub.3                              178                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  CH.sub.3                                                                              H   (CH.sub.3).sub.2 CH                   179                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  CH.sub.3                                                                              H   (CH.sub.3).sub.3 C                    180                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  CH.sub.3                                                                              H   (CH.sub.3).sub.2CHC(CH.sub.3).sub                                              .2                                    181                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  CH.sub.3                                                                              H   (CH.sub.3).sub.3 CCH.sub.2            182                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  CH.sub.3                                                                              H   CH.sub.3 OCH.sub.2C(CH.sub.3).sub                                              .2                                    183                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  CH.sub.3                                                                              H   ClCH.sub.2C(CH.sub.3).sub.2           184                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  CH.sub.3                                                                              H                                                                                   ##STR57##                            185                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  CH.sub.3                                                                              H   (CH.sub.3).sub.2 CCH                  186                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  CH.sub.3                                                                              H                                                                                   ##STR58##                            187                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  C.sub.2 H.sub.5                                                                       H   CH.sub.3                              188                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.2 CH                   189                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub. 3 H.sub.7 C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.3 C                    190                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.2CHC(CH.sub.3).sub                                              .2                                    191                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.3 CCH.sub.2            192                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  C.sub.2 H.sub.5                                                                       H   CH.sub.3 OCH.sub.2C(CH.sub.3).sub                                              .2                                    193                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  C.sub.2 H.sub.5                                                                       H   ClCH.sub.2C(CH.sub.3).sub.2           194                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  C.sub.2 H.sub.5                                                                       H                                                                                   ##STR59##                            195                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.2 CCH                  196                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  C.sub.2 H.sub.5                                                                       H                                                                                   ##STR60##                            197                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  C.sub.3 H.sub.7                                                                       H   CH.sub.3                              198                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  C.sub.3 H.sub.7                                                                       H   (CH.sub.3).sub.2 CH                   199                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  C.sub.3 H.sub.7                                                                       H   (CH.sub.3).sub.3 C                    200                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  C.sub.3 H.sub.7                                                                       H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   201                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  (CH.sub.3).sub.2 CH                                                                   H   CH.sub.3                              202                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  (CH.sub.3).sub.2 CH                                                                   H   (CH.sub.3).sub.2 CH                   203                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  (CH.sub.3).sub.2 CH                                                                   H   (CH.sub.3).sub.3 C                    204                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  (CH.sub.3).sub.2 CH                                                                   H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   205                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  CH.sub.3                                                                              CH.sub.3                                                                           CH.sub.3                              206                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  CH.sub.3                                                                              CH.sub.3                                                                           (CH.sub.3).sub.2 CH                   207                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  CH.sub.3                                                                              CH.sub.3                                                                           (CH.sub.3).sub.3 C                    208                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7  CH.sub.3                                                                              CH.sub.3                                                                           (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   209                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             H      H   CH.sub.3     75                       210                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             H      H   (CH.sub.3).sub.2 CH                                                                         80                       211                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             H      H   (CH.sub.3).sub.3 C                                                                          86                       212                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             H      H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2          108                      213                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             H      H   (CH.sub.3).sub.3 CCH.sub.2                                                                  74                       214                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             H      H   CH.sub.3 OCH.sub.2C(CH.sub.3).sub                                              .2           68                       215                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             H      H   ClCH.sub.2C(CH.sub.3).sub.2                                                                 153                      216                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             H      H                                                                                   ##STR61##                            217                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             H      H   (CH.sub.3).sub.2 CCH                                                                        67                       218                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             H      H                                                                                   ##STR62##                            219                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             H      H                                                                                   ##STR63##                            220                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             H      H                                                                                   ##STR64##                            221                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             H      H                                                                                   ##STR65##                            222                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             H      H                                                                                   ##STR66##                            223                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             H      H                                                                                   ##STR67##                            224                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             H      H                                                                                   ##STR68##                            225                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             H      H                                                                                   ##STR69##                            226                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             H      H                                                                                   ##STR70##                            227                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             H      H                                                                                   ##STR71##                            228                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             H      H                                                                                   ##STR72##                            229                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             H      H                                                                                   ##STR73##                            230                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             H      H                                                                                   ##STR74##                            231                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             CH.sub.3                                                                              H   CH.sub.3     oil                      232                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             CH.sub.3                                                                              H   (CH.sub.3).sub.2 CH                   233                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             CH.sub.3                                                                              H   (CH.sub.3).sub.3 C                                                                          94                       234                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             CH.sub.3                                                                              H   (CH.sub.3).sub.2CHC(CH.sub.3).sub                                              .2                                    235                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub. 2 CH                                                                            CH.sub.3                                                                              H   (CH.sub.3).sub.3 CCH.sub.2                                                                  oil                      236                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             CH.sub.3                                                                              H   CH.sub.3 OCH.sub.2C(CH.sub.3).sub                                              .2                                    237                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             CH.sub.3                                                                              H   ClCH.sub.2C(CH.sub.3).sub.2                                                                 112                      238                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             CH.sub.3                                                                              H                                                                                   ##STR75##                            239                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             CH.sub.3                                                                              H   (CH.sub.3).sub.2 CCH                  240                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             CH.sub.3                                                                              H                                                                                   ##STR76##                            241                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             C.sub.2 H.sub.5                                                                       H   CH.sub.3                              242                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             C.sub. 2 H.sub.5                                                                      H   (CH.sub.3).sub.2 CH                   243                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.3 C                    244                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.2CHC(CH.sub.3).sub                                              .2                                    245                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.3 CCH.sub.2            246                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             C.sub.2 H.sub.5                                                                       H   CH.sub.3 OCH.sub.2C(CH.sub.3).sub                                              .2                                    247                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             C.sub.2 H.sub.5                                                                       H   ClCH.sub.2C(CH.sub.3).sub.2           248                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             C.sub.2 H.sub.5                                                                       H                                                                                   ##STR77##                            249                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.2 CCH                  250                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             C.sub.2 H.sub.5                                                                       H                                                                                   ##STR78##                            251                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             C.sub.3 H.sub.7                                                                       H   CH.sub.3                              252                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             C.sub.3 H.sub.7                                                                       H   (CH.sub.3).sub.2 CH                   253                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             C.sub.3 H.sub.7                                                                       H   (CH.sub.3).sub.3 C                    254                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             C.sub.3 H.sub.7                                                                       H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   255                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             (CH.sub.3).sub.2 CH                                                                   H   CH.sub.3                              256                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             (CH.sub.3).sub.2 CH                                                                   H   (CH.sub. 3).sub.2 CH                  257                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             (CH.sub.3).sub.2 CH                                                                   H   (CH.sub.3).sub.3 C                    258                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             (CH.sub.3).sub.2 CH                                                                   H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   259                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             CH.sub.3                                                                              CH.sub.3                                                                           CH.sub.3                              260                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             CH.sub.3                                                                              CH.sub.3                                                                           (CH.sub.3).sub.2 CH                   261                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             CH.sub.3                                                                              CH.sub.3                                                                           (CH.sub.3).sub.3 C                    262                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                             CH.sub.3                                                                              CH.sub.3                                                                           (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   263                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.4 H.sub.9  H      H   CH.sub.3                              264                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.4 H.sub.9  H      H   (CH.sub.3).sub.2 CH                   265                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.4 H.sub.9  H      H   (CH.sub.3).sub.3 C                    266                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.4 H.sub.9  H      H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   267                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.4 H.sub.9  CH.sub.3                                                                              H   CH.sub.3                              268                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.4 H.sub.9  CH.sub.3                                                                              H   (CH.sub.3).sub.2 CH                   269                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.4 H.sub.9  CH.sub.3                                                                              H   (CH.sub.3).sub.3 C                    270                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.4 H.sub.9  CH.sub.3                                                                              H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   271                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CHCH.sub.2                                                                     H      H   CH.sub.3     oil                      272                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CHCH.sub.2                                                                     H      H   (CH.sub.3).sub.2 CH                                                                         oil                      273                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CHCH.sub.2                                                                     H      H   (CH.sub.3).sub.3 C                                                                          oil                      274                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CHCH.sub.2                                                                     H      H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2          oil                      275                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CHCH.sub.2                                                                     CH.sub.3                                                                              H   CH.sub.3     73                       276                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CHCH.sub.2                                                                     CH.sub.3                                                                              H   (CH.sub.3).sub.3 C                                                                          oil                      277                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CHCH.sub.2                                                                     CH.sub.3                                                                              H   (CH.sub.3).sub.3 CCH.sub.2                                                                  oil                      278                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CHCH.sub.2                                                                     CH.sub.3                                                                              H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   279                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR79##       H      H   CH.sub.3     oil                      280                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR80##       H      H   (CH.sub.3).sub.2 CH                                                                         66                       281                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR81##       H      H   (CH.sub.3).sub.3 C                                                                          99                       282                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR82##       H      H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2          66                       283                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR83##       CH.sub.3                                                                              H   CH.sub.3     oil                      284                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR84##       CH.sub.3                                                                              H   (CH.sub.3).sub.2 CH                   285                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR85##       CH.sub.3                                                                              H   (CH.sub.3).sub.3 C                                                                          100                      286                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR86##       CH.sub.3                                                                              H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   287                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.3 C                                                                              H      H   (CH.sub.3).sub.2 CH                                                                         oil                      288                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.3 C                                                                              H      H   (CH.sub.3).sub.3 C                                                                          85                       289                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.3 C                                                                              H      H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2          107                      290                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.3 CCH.sub.2                                                                      H      H   CH.sub.3     oil                      291                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.3 CCH.sub.2                                                                      H      H   (CH.sub.3).sub.2 CH                   292                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.3 CCH.sub.2                                                                      H      H   (CH.sub.3).sub.3 C                                                                          83                       293                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.3 CCH.sub.2                                                                      H      H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   294                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CHCH(CH.sub.3)                                                                 H      H   CH.sub.3                              295                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CHCH(CH.sub.3)                                                                 H      H   (CH.sub.3).sub.2 CH                   296                                                                               CH.sub.3                                                                          CH.sub. 3                                                                         6-CH.sub.3                                                                         (CH.sub.3).sub.2 CHCH(CH.sub.3)                                                                 H      H   (CH.sub.3).sub.3 C                    297                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CHCH(CH.sub.3)                                                                 H      H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   298                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CHCH(CH.sub.3)                                                                 H      H   CH.sub.3     oil                      299                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CHCH(CH.sub.3)                                                                 H      H   (CH.sub.3).sub.2 CH                   300                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CHCH(CH.sub.3)                                                                 H      H   (CH.sub.3).sub.3 C                                                                          92                       301                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CHCH(CH.sub.3)                                                                 H      H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   302                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.2CHCH.sub.2                                                                              H      H   CH.sub.3     oil                      303                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.2CHCH.sub.2                                                                              H      H   (CH.sub.3).sub.2 CH                                                                         oil                      304                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.2CHCH.sub.2                                                                              H      H   (CH.sub.3).sub.3 C                                                                          oil                      305                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.2CHCH.sub.2                                                                              H      H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2          oil                      306                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.2CHCH.sub.2                                                                              CH.sub.3                                                                              H   CH.sub.3                              307                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.2CHCH.sub.2                                                                              CH.sub.3                                                                              H   (CH.sub.3).sub.2 CH                   308                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.2CHCH.sub.2                                                                              CH.sub.3                                                                              H   (CH.sub.3).sub.3 C                    309                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.2CHCH.sub.2                                                                              CH.sub.3                                                                              H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   310                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR87##       H      H   CH.sub.3     oil                      311                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR88##       H      H   (CH.sub.3).sub.2 CH                                                                         35                       312                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR89##       H      H   (CH.sub.3).sub.3 C                                                                          75                       313                                                                               CH.sub.3                                                                          CH.sub. 3                                                                         6-CH.sub.3                                                                          ##STR90##       H      H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   314                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR91##       H      H   (CH.sub.3).sub.3 CCH.sub.2            315                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR92##       H      H   CH.sub.3 OCH.sub.2C(CH.sub.3).sub                                              .2                                    316                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR93##       H      H   ClCH.sub.2C(CH.sub.3).sub.2           317                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR94##       H      H                                                                                   ##STR95##                            318                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR96##       H      H   (CH.sub.3).sub.2 CCH                  319                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR97##       H      H                                                                                   ##STR98##                            320                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR99##       CH.sub.3                                                                              H   CH.sub.3     83                       321                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR100##      CH.sub.3                                                                              H   (CH.sub.3).sub.2 CH                   322                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR101##      CH.sub.3                                                                              H   (CH.sub.3).sub.3 C                                                                          oil                      323                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR102##      CH.sub.3                                                                              H   (CH.sub.3).sub.2CHC(CH.sub.3).sub                                              .2                                    324                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR103##      CH.sub.3                                                                              H   (CH.sub.3).sub.3 CCH.sub.2                                                                  oil                      325                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR104##      CH.sub.3                                                                              H   CH.sub.3 OCH.sub.2C(CH.sub.3).sub                                              .2                                    326                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR105##      CH.sub.3                                                                              H   ClCH.sub.2C(CH.sub.3).sub.2           327                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR106##      CH.sub.3                                                                              H                                                                                   ##STR107##                           328                                                                               CH.sub. 3                                                                         CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR108##      CH.sub.3                                                                              H   (CH.sub.3).sub.2 CCH                  329                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR109##      CH.sub.3                                                                              H                                                                                   ##STR110##                           330                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR111##      C.sub.2 H.sub.5                                                                       H   CH.sub.3                              331                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR112##      C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.2 CH                   332                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR113##      C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.3 C                    333                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR114##      C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.2CHC(CH.sub.3).sub                                              .2                                    334                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR115##      C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.3 CCH.sub.2            335                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR116##      C.sub.2 H.sub.5                                                                       H   CH.sub.3 OCH.sub.2C(CH.sub.3).sub                                              .2                                    336                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR117##      C.sub.2 H.sub.5                                                                       H   ClCH.sub.2C(CH.sub.3).sub.2           337                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR118##      C.sub.2 H.sub.5                                                                       H                                                                                   ##STR119##                           338                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR120##      C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.2 CCH                  339                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR121##      C.sub.2 H.sub.5                                                                       H                                                                                   ##STR122##                           340                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR123##      C.sub.3 H.sub.7                                                                       H   CH.sub.3                              341                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR124##      C.sub.3 H.sub.7                                                                       H   (CH.sub. 3).sub.2 CH                  342                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR125##      C.sub.3 H.sub.7                                                                       H   (CH.sub.3).sub.3 C                    343                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR126##      C.sub.3 H.sub.7                                                                       H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   344                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR127##      (CH.sub.3).sub.2 CH                                                                   H   CH.sub.3                              345                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR128##      (CH.sub.3).sub.2 CH                                                                   H   (CH.sub.3).sub.2 CH                   346                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR129##      (CH.sub.3).sub.2 CH                                                                   H   (CH.sub.3).sub.3 C                    347                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR130##      (CH.sub.3).sub.2 CH                                                                   H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   348                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR131##      CH.sub.3                                                                              CH.sub.3                                                                           CH.sub.3                              349                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub. 3                                                                         ##STR132##      CH.sub.3                                                                              CH.sub.3                                                                           (CH.sub.3).sub.2 CH                   350                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR133##      CH.sub.3                                                                              CH.sub.3                                                                           (CH.sub.3).sub.3 C                    351                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR134##      CH.sub.3                                                                              CH.sub.3                                                                           (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   352                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR135##      H      H   CH.sub.3     60                       353                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR136##      H      H   (CH.sub.3).sub.2 CH                                                                         oil                      354                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR137##      H      H   (CH.sub.3).sub.3 C                                                                          80                       355                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR138##      H      H   (CH.sub.3).sub.2CHC(CH.sub.3).sub                                              .2           85                       356                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR139##      H      H   (CH.sub.3).sub.3 CCH.sub.2                                                                  74                       357                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub. 3                                                                         ##STR140##      H      H   CH.sub.3 OCH.sub.2C(CH.sub.3).sub                                              .2                                    358                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR141##      H      H   ClCH.sub.2C(CH.sub.3).sub.2                                                                 94                       359                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR142##      H      H                                                                                   ##STR143##  39                       360                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR144##      H      H   (CH.sub.3).sub.2 CCH                                                                        oil                      361                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR145##      H      H                                                                                   ##STR146##                           362                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR147##      CH.sub.3                                                                              H   CH.sub.3     96                       363                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR148##      CH.sub.3                                                                              H   (CH.sub.3).sub.2 CH                                                                         oil                      364                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR149##      CH.sub.3                                                                              H   (CH.sub.3).sub.3 C                                                                          63                       365                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR150##      CH.sub.3                                                                              H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   366                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR151##      CH.sub.3                                                                              H   (CH.sub.3).sub.3 CCH.sub.2            367                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR152##      CH.sub.3                                                                              H   CH.sub.3 OCH.sub.2C(CH.sub.3).sub                                              .2                                    368                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR153##      CH.sub.3                                                                              H   ClCH.sub.2C(CH.sub.3).sub.2           369                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR154##      CH.sub.3                                                                              H                                                                                   ##STR155##                           370                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR156##      CH.sub.3                                                                              H   (CH.sub.3).sub.2 CCH                  371                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR157##      CH.sub.3                                                                              H                                                                                   ##STR158##                           372                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR159##      C.sub.2 H.sub.5                                                                       H   CH.sub.3                              373                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR160##      C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.2 CH                   374                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR161##      C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.3 C                    375                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR162##      C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.2CHC(CH.sub.3).sub                                              .2                                    376                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR163##      C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.3 CCH.sub.2            377                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR164##      C.sub.2 H.sub.5                                                                       H   CH.sub.3 OCH.sub.2C(CH.sub.3).sub                                              .2                                    378                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR165##      C.sub.2 H.sub. 5                                                                      H   ClCH.sub.2C(CH.sub.3).sub.2           379                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR166##      C.sub.2 H.sub.5                                                                       H                                                                                   ##STR167##                           380                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR168##      C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.2 CCH                  381                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR169##      C.sub.2 H.sub.5                                                                       H                                                                                   ##STR170##                           382                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR171##      C.sub.3 H.sub.7                                                                       H   CH.sub.3                              383                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR172##      C.sub.3 H.sub.7                                                                       H   (CH.sub.3).sub.2 CH                   384                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR173##      C.sub.3 H.sub.7                                                                       H   (CH.sub.3).sub.3 C                    385                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR174##      C.sub.3 H.sub.7                                                                       H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   386                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR175##      (CH.sub.3).sub.2 CH                                                                   H   CH.sub.3                              387                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR176##      (CH.sub.3).sub.2 CH                                                                   H   (CH.sub.3).sub.2 CH                   388                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR177##      (CH.sub.3).sub.2 CH                                                                   H   (CH.sub.3).sub.3 C                    389                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR178##      (CH.sub.3).sub.2 CH                                                                   H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   390                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR179##      CH.sub.3                                                                              CH.sub.3                                                                           CH.sub.3                              391                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR180##      CH.sub.3                                                                              CH.sub.3                                                                           (CH.sub.3).sub.2 CH                   392                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR181##      CH.sub.3                                                                              CH.sub.3                                                                           (CH.sub.3).sub.3 C                    393                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR182##      CH.sub.3                                                                              CH.sub.3                                                                           (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   394                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR183##      H      H   CH.sub.3     78                       395                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR184##      H      H   (CH.sub.3).sub.2 CH                                                                         oil                      396                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR185##      H      H   (CH.sub.3).sub.3 C                                                                          97                       397                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR186##      H      H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2          122                      398                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR187##      H      H   (CH.sub.3).sub.3 CCH.sub.2            399                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR188##      H      H   CH.sub.3 OCH.sub.2C(CH.sub.3).sub                                              .2                                    400                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR189##      H      H   ClCH.sub.2C(CH.sub.3 ).sub.2          401                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR190##      H      H                                                                                   ##STR191##                           402                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR192##      H      H   (CH.sub.3).sub.2 CCH                  403                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR193##      H      H                                                                                   ##STR194##                           404                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR195##      CH.sub.3                                                                              H   CH.sub.3     84                       405                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR196##      CH.sub.3                                                                              H   (CH.sub.3).sub.2 CH                                                                         oil                      406                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR197##      CH.sub.3                                                                              H   (CH.sub.3).sub.3 C                                                                          72                       407                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR198##      CH.sub.3                                                                              H   (CH.sub.3).sub.2CHC(CH.sub.3).sub                                              .2                                    408                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR199##      CH.sub.3                                                                              H   (CH.sub.3).sub.3 CCH.sub.2                                                                  118                      409                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR200##      CH.sub.3                                                                              H   CH.sub.3 OCH.sub.2C(CH.sub.3).sub                                              .2                                    410                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR201##      CH.sub.3                                                                              H   ClCH.sub.2C(CH.sub.3).sub.2                                                                 115                      411                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR202##      CH.sub.3                                                                              H                                                                                   ##STR203##                           412                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR204##      CH.sub.3                                                                              H   (CH.sub.3).sub.2 CCH                  413                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR205##      CH.sub.3                                                                              H                                                                                   ##STR206##                           414                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR207##      C.sub.2 H.sub.5                                                                       H   CH.sub.3                              415                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR208##      C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.2 CH                   416                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR209##      C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.3 C                    417                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR210##      C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   418                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR211##      C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.3 CCH.sub.2            419                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR212##      C.sub.2 H.sub.5                                                                       H   CH.sub.3 OCH.sub.2C(CH.sub.3).sub                                              .2                                    420                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR213##      C.sub.2 H.sub.5                                                                       H   ClCH.sub.2C(CH.sub.3).sub.2           421                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR214##      C.sub.2 H.sub.5                                                                       H                                                                                   ##STR215##                           422                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR216##      C.sub.2 H.sub.5                                                                       H   (CH.sub.3).sub.2 CCH                  423                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR217##      C.sub.2 H.sub.5                                                                       H                                                                                   ##STR218##                           424                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR219##      C.sub.3 H.sub.7                                                                       H   CH.sub.3                              425                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR220##      C.sub.3 H.sub.7                                                                       H   (CH.sub.3).sub.2 CH                   426                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR221##      C.sub.3 H.sub.7                                                                       H   (CH.sub.3).sub.3 C                    427                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR222##      C.sub.3 H.sub.7                                                                       H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   428                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR223##      (CH.sub.3 ).sub.2 CH                                                                  H   CH.sub.3                              429                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR224##      (CH.sub.3).sub.2 CH                                                                   H   (CH.sub.3).sub.2 CH                   430                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR225##      (CH.sub.3).sub.2 CH                                                                   H   (CH.sub.3).sub.3 C                    431                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR226##      (CH.sub.3).sub.2 CH                                                                   H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   432                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR227##      CH.sub.3                                                                              CH.sub.3                                                                           CH.sub.3                              433                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR228##      CH.sub.3                                                                              CH.sub.3                                                                           (CH.sub.3).sub.2 CH                   434                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR229##      CH.sub.3                                                                              CH.sub.3                                                                           (CH.sub.3).sub.3 C                    435                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR230##      CH.sub.3                                                                              CH.sub.3                                                                           (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   436                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR231##      H      H   CH.sub.3     oil                      437                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR232##      H      H   (CH.sub.3).sub.2 CH                   438                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR233##      H      H   (CH.sub.3).sub.3 C                                                                          104                      439                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR234##      H      H   (CH.sub.3).sub.2CHC(CH.sub.3).sub                                              .2                                    440                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3OCH.sub.2CH(CH.sub.3)                                                                   H      H   CH.sub.3     76                       441                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3OCH.sub.2CH(CH.sub.3)                                                                   H      H   (CH.sub.3).sub.2 CH                   442                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3OCH.sub.2CH(CH.sub.3)                                                                   H      H   (CH.sub.3).sub.3 C                                                                          oil                      443                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3OCH.sub.2CH(CH.sub.3)                                                                   H      H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2                                   444                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3 O (CH.sub.2).sub.2                                                                     H      H   CH.sub.3     oil                      445                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3 O(CH.sub.2).sub.2                                                                      H      H   (CH.sub.3).sub.2 CH                                                                         oil                      446                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3 O(CH.sub.2).sub.2                                                                      H      H   (CH.sub.3).sub.3 C                                                                          oil                      447                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3 O(CH.sub.2).sub.2                                                                      H      H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2          oil                      448                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3 O(CH.sub.2).sub.2                                                                      CH.sub.3                                                                              H   CH.sub.3     oil                      449                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3 O(CH.sub.2).sub.2                                                                      CH.sub.3                                                                              H   (CH.sub.3).sub.2 CH                                                                         oil                      450                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3 O(CH.sub.2).sub.2                                                                      CH.sub.3                                                                              H   (CH.sub.3).sub.3 C                                                                          oil                      451                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3 O(CH.sub.2).sub.2                                                                      CH.sub.3                                                                              H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2          oil                      452                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub. 3 O(CH.sub.2).sub.3                                                                     H      H   CH.sub.3     oil                      453                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3 O(CH.sub.2).sub.3                                                                      H      H   (CH.sub.3).sub.2 CH                                                                         oil                      454                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3 O(CH.sub.2).sub.3                                                                      H      H   (CH.sub.3).sub.3 C                                                                          oil                      455                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3 O(CH.sub.2).sub.3                                                                      H      H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2          oil                      455                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3 O(CH.sub.2).sub.3                                                                      CH.sub.3                                                                              H   CH3          oil                      457                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3 O(CH.sub.2).sub.3                                                                      CH.sub.3                                                                              H   (CH.sub.3).sub.2 CH                                                                         oil                      458                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3 O(CH.sub.2).sub.3                                                                      CH.sub.3                                                                              H   (CH.sub.3).sub.3 C                                                                          oil                      459                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3 O(CH.sub.2).sub.3                                                                      CH.sub.3                                                                              H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2          oil                      460                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5 O(CH.sub.2).sub.2CH(CH.sub.3)                                                   H      H   CH.sub.3     oil                      461                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5 O(CH.sub.2).sub.2CH(CH.sub.3)                                                   H      H   (CH.sub.3).sub.2 CH                                                                         oil                      462                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5 O(CH.sub.2).sub.2CH(CH.sub.3)                                                   H      H   (CH.sub.3).sub.3 C                                                                          oil                      463                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5 O(CH.sub.2).sub.2CH(CH.sub.3)                                                   H      H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2          oil                      464                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3 OCH.sub.2CH(CH.sub.3)CH                                                                H      H   CH.sub.3     oil                      465                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3 OCH.sub.2CH(CH.sub.3)CH                                                                H      H   (CH.sub.3).sub.2 CH                                                                         oil                      466                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3 OCH.sub.2CH(CH.sub.3)CH                                                                H      H   (CH.sub.3).sub.3 C                                                                          oil                      467                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3 OCH.sub.2CH(CH.sub.3) CH                                                               H      H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2          oil                      468                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5S(CH.sub.2).sub.2                                                                H      H   CH.sub.3     oil                      469                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5S(CH.sub.2).sub.2                                                                H      H   (CH.sub.3).sub.2 CH                                                                         oil                      470                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5S(CH.sub.2).sub.2                                                                H      H   (CH.sub.3).sub.3 C                                                                          oil                      471                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5S(CH.sub.2).sub.2                                                                H      H   (CH.sub.3).sub.2 CHC(CH.sub.3).su                                              b.2          oil                      __________________________________________________________________________

                                      TABLE 3                                      __________________________________________________________________________      ##STR235##                                     (Ic)                           Ex.                                                                            No.                                                                               X  Y  Z.sub.n                                                                            A              B      C*                                                                               R.sup.1   mp °C.                   __________________________________________________________________________     472                                                                               CH.sub.3                                                                          CH.sub.3                                                                          5-CH.sub.3                                                                         CH.sub.3       H      H CH.sub.3                                  473                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3       H      H C.sub.2 H.sub.5                           474                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3       H      H (CH.sub.3).sub.2 CH                       475                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3       H      H (CH.sub.3).sub.2 CHCH.sub.2               476                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3       H      H                                                                                 ##STR236##                               477                                                                               CH.sub.3                                                                          CH.sub. 3                                                                         6-CH.sub.3                                                                         CH.sub.3       H      H (CH.sub.3).sub.3 CCH.sub.2                478                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3       H      H                                                                                 ##STR237##                               479                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3       H      H                                                                                 ##STR238##                               480                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3       CH.sub.3                                                                              H CH.sub.3                                  481                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3       CH.sub.3                                                                              H C.sub.2 H.sub.5                                                                          oil                             482                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3       CH.sub.3                                                                              H (CH.sub.3).sub.2 CH                                                                      oil                             483                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3       CH.sub.3                                                                              H (CH.sub.3).sub.2 CHCH.sub.2                                                              oil                             484                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3       CH.sub.3                                                                              H                                                                                 ##STR239##                                                                              oil                             485                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3       CH.sub.3                                                                              H (CH.sub.3).sub.3 CCH.sub.2                                                               146                             486                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3       CH.sub.3                                                                              H                                                                                 ##STR240##                               487                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3       CH.sub.3                                                                              H                                                                                 ##STR241##                               488                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3       C.sub.2 H.sub.5                                                                       H CH.sub.3                                  489                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3       C.sub.2 H.sub.5                                                                       H C.sub.2 H.sub.5                           490                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3       C.sub.2 H.sub.5                                                                       H (CH.sub.3).sub.2 CH                       491                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3       C.sub.2 H.sub.5                                                                       H (CH.sub.3).sub.2 CHCH.sub.2               492                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3       C.sub.2 H.sub.5                                                                       H                                                                                 ##STR242##                               493                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3       C.sub.2 H.sub.5                                                                       H (CH.sub.3).sub.3 CCH.sub.2                494                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3       C.sub.2 H.sub.5                                                                       H                                                                                 ##STR243##                               495                                                                               CH.sub. 3                                                                         CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3       C.sub.2 H.sub.5                                                                       H                                                                                 ##STR244##                               496                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3       C.sub.3 H.sub.7                                                                       H C.sub.2 H.sub.5                           497                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3       C.sub.3 H.sub.7                                                                       H (CH.sub.3).sub.2 CH                       498                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3       C.sub.3 H.sub.7                                                                       H (CH.sub.3).sub.2 CHCH.sub.2               499                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3       C.sub.3 H.sub.7                                                                       H                                                                                 ##STR245##                               500                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3       (CH.sub.3).sub.2 CH                                                                   H (CH.sub.3).sub.3 CCH.sub.2                501                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3       (CH.sub.3).sub.2 CH                                                                   H C.sub.2 H.sub.5                           502                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3       (CH.sub.3).sub.2 CH                                                                   H (CH.sub.3).sub.2 CH                       503                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3       (CH.sub. 3).sub.2 CH                                                                  H (CH.sub.3).sub.2 CHCH.sub.2               504                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3       (CH.sub.3).sub.2 CH                                                                   H                                                                                 ##STR246##                               505                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3       (CH.sub.3).sub.2 CH                                                                   H (CH.sub.3).sub.3 CCH.sub.2                506                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               H      H CH.sub.3                                  507                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               H      H C.sub.2 H.sub.5                           508                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               H      H (CH.sub.3).sub.2 CH                                                                      oil                             509                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               H      H (CH.sub.3).sub.2 CHCH.sub.2               510                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               H      H                                                                                 ##STR247##                               511                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               H      H (CH.sub.3).sub.3 CCH.sub.2                512                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               H      H                                                                                 ##STR248##                               513                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               H      H                                                                                 ##STR249##                               514                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               CH.sub.3                                                                              H CH.sub.3                                  515                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               CH.sub.3                                                                              H C.sub.2 H.sub.5                                                                          oil                             516                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               CH.sub.3                                                                              H (CH.sub.3).sub.2 CH                       517                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               CH.sub.3                                                                              H (CH.sub.3).sub.2 CHCH.sub.2               518                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               CH.sub.3                                                                              H                                                                                 ##STR250##                               519                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               CH.sub.3                                                                              H (CH.sub.3).sub.3 CCH.sub.2                520                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               CH.sub.3                                                                              H                                                                                 ##STR251##                               521                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               CH.sub.3                                                                              H                                                                                 ##STR252##                               522                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               C.sub.2 H.sub.5                                                                       H CH.sub.3                                  523                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               C.sub.2 H.sub.5                                                                       H C.sub.2 H.sub.5                           524                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               C.sub.2 H.sub.5                                                                       H (CH.sub.3).sub.2 CH                       525                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               C.sub.2 H.sub.5                                                                       H (CH.sub.3).sub.2 CHCH.sub.2               526                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               C.sub.2 H.sub.5                                                                       H                                                                                 ##STR253##                               527                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               C.sub.2 H.sub.5                                                                       H (CH.sub.3).sub.3 CCH.sub.2                528                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               C.sub.2 H.sub.5                                                                       H                                                                                 ##STR254##                               529                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               C.sub.2 H.sub.5                                                                       H                                                                                 ##STR255##                               530                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               C.sub.3 H.sub.7                                                                       H C.sub.2 H.sub.5                           531                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               C.sub.3 H.sub.5                                                                       H (CH.sub.3).sub.2 CH                       532                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               C.sub.3 H.sub.7                                                                       H (CH.sub.3).sub.2 CHCH.sub.2               533                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               C.sub.3 H.sub.7                                                                       H                                                                                 ##STR256##                               534                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               (CH.sub.3).sub.2 CH                                                                   H (CH.sub.3).sub.3 CCH.sub.2                535                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               (CH.sub.3).sub.2 CH                                                                   H C.sub.2 H.sub.5                           536                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               (CH.sub.3).sub.2 CH                                                                   H (CH.sub.3).sub.2 CH                       537                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               (CH.sub.3).sub.2 CH                                                                   H (CH.sub.3).sub.2 CHCH.sub.2               538                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               (CH.sub.3).sub.2 CH                                                                   H                                                                                 ##STR257##                               539                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               (CH.sub.3).sub.2 CH                                                                   H (CH.sub.3).sub.3 CCH.sub.2                540                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7                                                                               H      H CH.sub.3                                  541                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7                                                                               H      H C.sub.2 H.sub.5                           542                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7                                                                               H      H (CH.sub.3).sub.2 CH                       543                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7                                                                               H      H (CH.sub.3).sub.2 CHCH.sub.2               544                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7                                                                               H      H                                                                                 ##STR258##                               545                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7                                                                               H      H (CH.sub.3).sub.3 CCH.sub.2                546                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7                                                                               H      H                                                                                 ##STR259##                               547                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7                                                                               H      H                                                                                 ##STR260##                               548                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7                                                                               CH.sub.3                                                                              H CH.sub.3                                  549                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7                                                                               CH.sub.3                                                                              H C.sub.2 H.sub.5                           550                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7                                                                               CH.sub.3                                                                              H (CH.sub.3).sub.2 CH                       551                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7                                                                               CH.sub.3                                                                              H (CH.sub.3).sub.2 CHCH.sub.2               552                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7                                                                               CH.sub.3                                                                              H                                                                                 ##STR261##                               553                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7                                                                               CH.sub.3                                                                              H (CH.sub.3).sub.3 CCH.sub.2                554                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               CH.sub.3                                                                              H                                                                                 ##STR262##                               555                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.2 H.sub.5                                                                               CH.sub.3                                                                              H                                                                                 ##STR263##                               556                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7                                                                               C.sub.2 H.sub.5                                                                       H CH.sub.3                                  557                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7                                                                               C.sub.2 H.sub.5                                                                       H C.sub.2 H.sub.5                           558                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7                                                                               C.sub.2 H.sub.5                                                                       H (CH.sub.3).sub.2 CH                       559                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7                                                                               C.sub.2 H.sub.5                                                                       H (CH.sub.3).sub.2 CHCH.sub.2               560                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7                                                                               C.sub.2 H.sub.5                                                                       H                                                                                 ##STR264##                               561                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7                                                                               C.sub.2 H.sub.5                                                                       H (CH.sub.3).sub.3 CCH.sub.2                562                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7                                                                               C.sub.2 H.sub.5                                                                       H                                                                                 ##STR265##                               563                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7                                                                               C.sub.2 H.sub.5                                                                       H                                                                                 ##STR266##                               564                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7                                                                               C.sub.3 H.sub.7                                                                       H C.sub.2 H.sub.5                           565                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7                                                                               C.sub.3 H.sub.7                                                                       H (CH.sub.3).sub.2 CH                       566                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7                                                                               C.sub.3 H.sub.7                                                                       H (CH.sub.3).sub.2 CHCH.sub.2               567                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7                                                                               C.sub.3 H.sub.7                                                                       H                                                                                 ##STR267##                               568                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7                                                                               C.sub.3 H.sub.7                                                                       H (CH.sub.3).sub.3 CCH.sub.2                569                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7                                                                               (CH.sub.3).sub.2 CH                                                                   H C.sub.2 H.sub.5                           570                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7                                                                               (CH.sub.3).sub.2 CH                                                                   H (CH.sub.3).sub.2 CH                       571                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7                                                                               (CH.sub.3).sub.2 CH                                                                   H (CH.sub.3).sub.2 CHCH.sub.2               572                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7                                                                               (CH.sub.3).sub.2 CH                                                                   H                                                                                 ##STR268##                               573                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.3 H.sub.7                                                                               (CH.sub.3).sub.2 CH                                                                   H (CH.sub.3).sub.3 CCH.sub.2                574                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                           H      H CH.sub.3  67                              575                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                           H      H C.sub.2 H.sub.5                                                                          87                              576                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                           H      H (CH.sub.3).sub.2 CHCH.sub.2                                                              41                              577                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                           H      H                                                                                 ##STR269##                                                                              83                              578                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                           H      H (CH.sub.3).sub.3 CCH.sub.2                                                               oil                             579                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                           H      H                                                                                 ##STR270##                               580                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                           CH.sub.3                                                                              H CH.sub.3                                  581                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                           CH.sub.3                                                                              H C.sub.2 H.sub.5                           582                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                           CH.sub.3                                                                              H (CH.sub.3).sub.2 CH                       583                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                           CH.sub.3                                                                              H (CH.sub.3).sub.2 CHCH.sub.2               584                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                           CH.sub.3                                                                              H                                                                                 ##STR271##                               585                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                           CH.sub.3                                                                              H (CH.sub.3).sub.3 CCH.sub.2                                                               83                              586                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                           CH.sub.3                                                                              H                                                                                 ##STR272##                               587                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                           CH.sub.3                                                                              H                                                                                 ##STR273##                               588                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                           C.sub.2 H.sub.5                                                                       H CH.sub.3                                  589                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                           C.sub.2 H.sub.5                                                                       H C.sub.2 H.sub.5                           590                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                           C.sub.2 H.sub.5                                                                       H (CH.sub.3).sub.2 CH                       591                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                           C.sub.2 H.sub.5                                                                       H (CH.sub.3).sub.2 CHCH.sub.2               592                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                           C.sub.2 H.sub.5                                                                       H                                                                                 ##STR274##                               593                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                           C.sub.2 H.sub.5                                                                       H (CH.sub.3).sub.3 CCH.sub.2                594                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                           C.sub.2 H.sub.5                                                                       H                                                                                 ##STR275##                               595                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                           C.sub.2 H.sub.5                                                                       H                                                                                 ##STR276##                               596                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                           C.sub.3 H.sub.7                                                                       H C.sub.2 H.sub.5                           597                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                           C.sub.3 H.sub.7                                                                       H (CH.sub.3).sub.2 CH                       598                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                           C.sub.3 H.sub.7                                                                       H (CH.sub.3).sub.2 CHCH.sub.2               599                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                           C.sub.3 H.sub.7                                                                       H                                                                                 ##STR277##                               600                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                           C.sub.3 H.sub.7                                                                       H (CH.sub.3).sub.3 CCH.sub.2                601                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                           (CH.sub.3).sub.2 CH                                                                   H C.sub.2 H.sub.5                           602                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                           (CH.sub.3).sub.2 CH                                                                   H (CH.sub.3).sub.2 CH                       603                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                           (CH.sub.3).sub.2 CH                                                                   H (CH.sub.3).sub.2 CHCH.sub.2               604                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                           (CH.sub.3).sub.2 CH                                                                   H                                                                                 ##STR278##                               605                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CH                                                                           (CH.sub.3).sub.2 CH                                                                   H (CH.sub.3).sub.3 CCH.sub.2                606                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.4 H.sub.9                                                                               H      H C2H.sub.5                                 607                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.4 H.sub.9                                                                               H      H (CH.sub.3).sub. 2 CH                      608                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.4 H.sub.9                                                                               H      H (CH.sub.3).sub.2 CHCH.sub.2               609                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.4 H.sub.9                                                                               H      H                                                                                 ##STR279##                               610                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.4 H.sub.9                                                                               H      H (CH.sub.3).sub.3 CCH.sub.2                611                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.4 H.sub.9                                                                               CH.sub.3                                                                              H C.sub.2 H.sub.5                           612                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.4 H.sub.9                                                                               CH.sub.3                                                                              H (CH.sub.3).sub.2 CH                       613                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.4 H.sub.9                                                                               CH.sub.3                                                                              H (CH.sub.3).sub.2 CHCH.sub.2               614                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.4 H.sub.9                                                                               CH.sub.3                                                                              H                                                                                 ##STR280##                               615                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         C.sub.4 H.sub.9                                                                               CH.sub.3                                                                              H (CH.sub.3).sub.3 CCH.sub.2                616                                                                               CH.sub. 3                                                                         CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CHCH.sub.2                                                                   H      H C.sub.2 H.sub.5                           617                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CHCH.sub.2                                                                   H      H (CH.sub.3).sub.2 CH                       618                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CHCH.sub.2                                                                   H      H (CH.sub.3).sub.2 CHCH.sub.2               619                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CHCH.sub.2                                                                   H      H                                                                                 ##STR281##                               620                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CHCH.sub.2                                                                   H      H (CH.sub.3).sub.3 CCH.sub.2                621                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CHCH.sub.2                                                                   CH.sub.3                                                                              H C.sub.2 H.sub.5                           622                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CHCH.sub.2                                                                   CH.sub.3                                                                              H (CH.sub.3).sub.2 CH                       623                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CHCH.sub.2                                                                   CH.sub.3                                                                              H (CH.sub.3).sub.2 CHCH.sub.2               624                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CHCH.sub.2                                                                   CH.sub.3                                                                              H                                                                                 ##STR282##                               625                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         (CH.sub.3).sub.2 CHCH.sub.2                                                                   CH.sub.3                                                                              H (CH.sub.3).sub.2 CHCH.sub.2               626                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR283##    H      H C.sub.2 H.sub.5                           627                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR284##    H      H (CH.sub.3).sub.2 CH                       628                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR285##    H      H (CH.sub.3).sub.2 CHCH.sub.2               629                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR286##    H      H                                                                                 ##STR287##                               630                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR288##    H      H (CH.sub.3).sub.3 CCH.sub.2                631                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR289##    CH.sub.3                                                                              H C.sub.2 H.sub.5                           632                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR290##    CH.sub.3                                                                              H (CH.sub.3).sub.2 CH                       633                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR291##    CH.sub.3                                                                              H (CH.sub.3).sub.2 CHCH.sub.2               634                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR292##    CH.sub.3                                                                              H                                                                                 ##STR293##                               635                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR294##    CH.sub.3                                                                              H (CH.sub.3).sub.3 CCH.sub.2                636                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.2CHCH.sub.2                                                                            H      H C.sub.2 H.sub.5                           637                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.2CHCH.sub.2                                                                            H      H (CH.sub.3).sub.2 CH                                                                      oil                             638                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.2CHCH.sub.2                                                                            H      H (CH.sub.3).sub.2 CHCH.sub.2               639                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.2CHCH.sub.2                                                                            H      H                                                                                 ##STR295##                               640                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.2CHCH.sub.2                                                                            H      H (CH.sub.3).sub.3 CCH.sub.2                641                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR296##    H      H C.sub.2 H.sub.5                           642                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR297##    H      H (CH.sub.3).sub.2 CH                                                                      oil                             643                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR298##    H      H (CH.sub.3).sub.2 CHCH.sub.2               644                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR299##    H      H                                                                                 ##STR300##                               645                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR301##    H      H (CH.sub.3).sub.3 CCH.sub.2                646                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR302##    H      H CH.sub.3                                  647                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR303##    H      H C.sub.2 H.sub.5                           648                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR304##    H      H (CH.sub.3).sub.2 CH                       649                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR305##    H      H (CH.sub.3).sub.2 CHCH.sub.2               650                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR306##    H      H                                                                                 ##STR307##                                                                              oil                             651                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR308##    H      H (CH.sub.3).sub.3 CCH.sub.2                652                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR309##    H      H                                                                                 ##STR310##                               653                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR311##    H      H                                                                                 ##STR312##                               654                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR313##    CH.sub.3                                                                              H CH.sub.3                                  655                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR314##    CH.sub.3                                                                              H C.sub.2 H.sub.5                           656                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR315##    CH.sub.3                                                                              H (CH.sub.3).sub.2 CH                       657                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR316##    CH.sub.3                                                                              H (CH.sub.3).sub.2 CHCH.sub.2               658                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR317##    CH.sub.3                                                                              H                                                                                 ##STR318##                               659                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR319##    CH.sub.3                                                                              H (CH.sub.3).sub.3 CCH.sub.2                660                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR320##    CH.sub.3                                                                              H                                                                                 ##STR321##                               661                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR322##    CH.sub.3                                                                              H                                                                                 ##STR323##                               662                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR324##    C.sub.2 H.sub.5                                                                       H CH.sub.3                                  663                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR325##    C.sub.2 H.sub.5                                                                       H C.sub.2 H.sub.5                           664                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR326##    C.sub.2 H.sub.5                                                                       H (CH.sub.3).sub.2 CH                       665                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR327##    C.sub.2 H.sub.5                                                                       H (CH.sub.3).sub.2 CHCH.sub.2               666                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR328##    C.sub.2 H.sub.5                                                                       H                                                                                 ##STR329##                                                                              oil                             667                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR330##    C.sub.2 H.sub.5                                                                       H (CH.sub.3).sub.3 CCH.sub.2                668                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR331##    C.sub.2 H.sub.5                                                                       H                                                                                 ##STR332##                               669                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR333##    C.sub.2 H.sub.5                                                                       H                                                                                 ##STR334##                               670                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR335##    C.sub.3 H.sub.7                                                                       H C.sub.2 H.sub.5                           671                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR336##    C.sub.3 H.sub.7                                                                       H (CH.sub.3).sub.2 CH                       672                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR337##    C.sub.3 H.sub.7                                                                       H (CH.sub.3).sub.2 CHCH.sub.2               673                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR338##    C.sub.3 H.sub.7                                                                       H                                                                                 ##STR339##                               674                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR340##    C.sub.3 H.sub.7                                                                       H (CH.sub.3).sub.3 CCH.sub.2                675                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR341##    (CH.sub.3).sub.2 CH                                                                   H C.sub.2 H5                                676                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR342##    (CH.sub.3).sub.2 CH                                                                   H (CH.sub.3).sub.2 CH                       677                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR343##    (CH.sub.3).sub.2 CH                                                                   H (CH.sub.3).sub.2 CHCH.sub.2               678                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR344##    (CH.sub.3).sub.2 CH                                                                   H                                                                                 ##STR345##                               679                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR346##    (CH.sub.3).sub.2 CH                                                                   H (CH.sub.3).sub.3 CCH.sub.2                680                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR347##    H      H CH.sub.3  70                              681                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR348##    H      H C.sub.2 H.sub.5                                                                          56                              682                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR349##    H      H (CH.sub.3).sub.2 CH                                                                      84                              683                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR350##    H      H (CH.sub.3).sub.2 CHCH.sub.2                                                              69                              684                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR351##    H      H                                                                                 ##STR352##                                                                              64                              685                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR353##    H      H (CH.sub.3).sub.3 CCH.sub.2                                                               114                             686                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR354##    H      H                                                                                 ##STR355##                               687                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR356##    H      H                                                                                 ##STR357##                               688                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR358##    CH.sub.3                                                                              H CH.sub.3                                  689                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR359##    CH.sub.3                                                                              H C.sub.2 H.sub.5                           690                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR360##    CH.sub.3                                                                              H (CH.sub.3).sub.2 CH                       691                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR361##    CH.sub.3                                                                              H (CH.sub.3).sub.2 CHCH.sub.2               692                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR362##    CH.sub.3                                                                              H                                                                                 ##STR363##                               693                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR364##    CH.sub.3                                                                              H (CH.sub.3).sub.3 CCH.sub.2                694                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR365##    CH.sub.3                                                                              H                                                                                 ##STR366##                               695                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR367##    CH.sub.3                                                                              H                                                                                 ##STR368##                               696                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR369##    C.sub.2 H.sub.5                                                                       H CH.sub.3                                  697                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR370##    C.sub.2 H.sub.5                                                                       H C.sub.2 H.sub.5                           698                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR371##    C.sub.2 H.sub.5                                                                       H (CH.sub.3).sub.2 CH                       699                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR372##    C.sub.2 H.sub.5                                                                       H (CH.sub.3).sub.2 CHCH.sub.2               700                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR373##    C.sub.2 H.sub.5                                                                       H                                                                                 ##STR374##                               701                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR375##    C.sub.2 H.sub.5                                                                       H (CH.sub.3).sub.3 CCH.sub.2                702                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR376##    C.sub.2 H.sub.5                                                                       H                                                                                 ##STR377##                               703                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR378##    C.sub.2 H.sub.5                                                                       H                                                                                 ##STR379##                               704                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR380##    C.sub.3 H.sub.7                                                                       H C.sub.2 H.sub.5                           705                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR381##    C.sub.3 H.sub.7                                                                       H (CH.sub.3).sub.2 CH                       706                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR382##    C.sub.3 H.sub.7                                                                       H (CH.sub.3).sub.2 CHCH.sub.2               707                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR383##    C.sub.3 H.sub.7                                                                       H                                                                                 ##STR384##                               708                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR385##    C.sub.3 H.sub.7                                                                       H (CH.sub.3).sub.3 CCH.sub.2                709                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR386##    (CH.sub.3).sub.2 CH                                                                   H C2H.sub.5                                 710                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR387##    (CH.sub.3).sub.2 CH                                                                   H (CH.sub.3).sub.2 CH                       711                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR388##    (CH.sub.3).sub.2 CH                                                                   H (CH.sub.3).sub.2 CHCH.sub.2               712                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR389##    (CH.sub.3).sub.2 CH                                                                   H                                                                                 ##STR390##                               713                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR391##    (CH.sub.3).sub.2 CH                                                                   H (CH.sub.3).sub.3 CCH.sub.2                714                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR392##    H      H CH.sub.3                                  715                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR393##    H      H C.sub.2 H.sub.5                           716                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR394##    H      H (CH.sub.3).sub.2 CH                       717                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR395##    H      H (CH.sub.3).sub.2 CHCH.sub.2               718                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR396##    H      H                                                                                 ##STR397##                               719                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR398##    H      H (CH.sub.3).sub.3 CCH.sub.2                720                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR399##    H      H                                                                                 ##STR400##                               721                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR401##    H      H                                                                                 ##STR402##                               722                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR403##    CH.sub.3                                                                              H CH.sub.3                                  723                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR404##    CH.sub.3                                                                              H C.sub.2 H.sub.5                           724                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR405##    CH.sub.3                                                                              H (CH.sub.3).sub.2 CH                       725                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR406##    CH.sub.3                                                                              H (CH.sub.3).sub.2 CHCH.sub.2               726                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR407##    CH.sub.3                                                                              H                                                                                 ##STR408##                               727                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR409##    CH.sub.3                                                                              H (CH.sub.3).sub.3 CCH.sub.2                728                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR410##    CH.sub.3                                                                              H                                                                                 ##STR411##                               729                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR412##    CH.sub.3                                                                              H                                                                                 ##STR413##                               730                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR414##    C.sub.2 H.sub.5                                                                       H CH.sub.3                                  731                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR415##    C.sub.2 H.sub.5                                                                       H C.sub.2 H.sub.5                           732                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR416##    C.sub.2 H.sub.5                                                                       H (CH.sub.3).sub.2 CH                       733                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR417##    C.sub.2 H.sub.5                                                                       H (CH.sub.3).sub.2 CHCH.sub.2               734                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR418##    C.sub.2 H.sub.5                                                                       H                                                                                 ##STR419##                               735                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR420##    C.sub.2 H.sub.5                                                                       H (CH.sub.3).sub.3 CCH.sub.2                736                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR421##    C.sub.2 H.sub.5                                                                       H                                                                                 ##STR422##                               737                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR423##    C.sub.2 H.sub.5                                                                       H                                                                                 ##STR424##                               738                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR425##    C.sub.3 H.sub.7                                                                       H C.sub.2 H.sub.5                           739                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR426##    C.sub.3 H.sub.7                                                                       H (CH.sub.3).sub.2 CH                       740                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR427##    C.sub.3 H.sub.7                                                                       H (CH.sub.3).sub.2 CHCH.sub.2               741                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR428##    C.sub.3 H.sub.7                                                                       H                                                                                 ##STR429##                               742                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR430##    C.sub.3 H.sub.7                                                                       H (CH.sub.3).sub.3 CCH.sub.2                743                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR431##    (CH.sub.3).sub.2 CH                                                                   H C.sub.2 H.sub.5                           744                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR432##    (CH.sub.3).sub.2 CH                                                                   H (CH.sub.3).sub.2 CH                       745                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR433##    (CH.sub.3).sub.2 CH                                                                   H (CH.sub.3).sub.2 CHCH.sub.2               746                                                                               CH.sub. 3                                                                         CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR434##    (CH.sub.3).sub.2 CH                                                                   H                                                                                 ##STR435##                               747                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                          ##STR436##    (CH.sub.3).sub.2 CH                                                                   H (CH.sub.3).sub.3 CCH.sub.2                748                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3O(CH.sub.2).sub.2                                                                     H      H C.sub.2 H.sub.5                           749                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3O(CH.sub.2).sub.2                                                                     H      H (CH.sub.3).sub.2 CH                       750                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3O(CH.sub.2).sub.3                                                                     H      H (CH.sub.3).sub.2 CHCH.sub.2               751                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3O(CH.sub.2).sub.2                                                                     H      H                                                                                 ##STR437##                               752                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3O(CH.sub.2).sub.2                                                                     H      H (CH.sub.3).sub.3 CCH.sub.2                753                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3O (CH.sub.2).sub.2                                                                    CH.sub.3                                                                              H C.sub.2 H.sub.5                           754                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3O(CH.sub.2).sub.2                                                                     CH.sub.3                                                                              H (CH.sub.3).sub.2 CH                       755                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3O(CH.sub.2).sub.2                                                                     CH.sub.3                                                                              H (CH.sub.3).sub.2 CHCH.sub.2                                                              57                              756                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3O(CH.sub.2).sub.2                                                                     CH.sub.3                                                                              H                                                                                 ##STR438##                                                                              54                              757                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3O(CH.sub.2).sub.2                                                                     CH.sub.3                                                                              H (CH.sub.3).sub.3 CCH.sub.2                758                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3OCH.sub.2CH(CH.sub.3)                                                                 H      H C.sub.2 H.sub.5                                                                          60                              759                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3OCH.sub.2CH(CH.sub.3)                                                                 H      H (CH.sub.3).sub.2 CH                       760                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3OCH.sub.2CH(CH.sub.3)                                                                 H      H (CH.sub.3).sub.2 CHCH.sub.2               761                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3OCH.sub.2CH(CH.sub.3)                                                                 H      H                                                                                 ##STR439##                               762                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3OCH.sub.2CH(CH.sub.3)                                                                 H      H (CH.sub.3).sub.3 CCH.sub.2                763                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3OCH.sub.2CH(CH.sub.3)                                                                 CH.sub.3                                                                              H C.sub.2 H.sub.5                           764                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3OCH.sub.2CH(CH.sub.3)                                                                 CH.sub.3                                                                              H (CH.sub.3).sub.2 CH                       765                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3OCH.sub.2CH(CH.sub.3)                                                                 CH.sub.3                                                                              H (CH.sub.3).sub.2 CHCH.sub.2               766                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3OCH.sub.2CH(CH.sub.3)                                                                 CH.sub.3                                                                              H                                                                                 ##STR440##                               767                                                                               CH.sub.3                                                                          CH.sub.3                                                                          6-CH.sub.3                                                                         CH.sub.3OCH.sub.2CH(CH.sub.3)                                                                 CH.sub.3                                                                              H (CH.sub.3).sub.3 CCH.sub.2                __________________________________________________________________________

Preparation of the intermediates EXAMPLE I ##STR441##

11.25 g (0.15 mol) of sarcosine and 3 g (0.075 mol) of NaOH are dissolved in 210 ml of water. While cooking the solution in a water bath 9 g (0.225 mol) of NaOH, dissolved in 45 ml of water, and 29.6 g (0.15 mol) of mesityleneacetyl chloride are added synchronously dropwise, during which addition the temperature is kept at <40 ° C. After 1 hour the mixture is acidified with concentrated HCI at 0° to 20° C., filtered off and the filtrate is dried in vacuo over P₂ O₅ at 70° C. 37.1 g (99.3 % of theory) of N-(2,4,6-trimethyl-phenyl-acetyl)-sarcosine of a melting point of 140° C. are obtained.

EXAMPLE II ##STR442##

37.1 g (0.149 mol) of N-(2,4,6-trimethyl-phenyl-acetyl)-sarcosine are suspended in 150 ml of methanol, 22 ml (0.165 mol) of dimethoxypropane are added and, after adding 1,43 g (7 5 mmol) of p-toluenesulphonic acid monohydrate,the mixture is refluxed for 3 hours.

After evaporating off the solvent, the residue is taken up in CH₂ Cl₂, washed with bicarbonate solution, dried and evaporated on a rotary evaporator. 34 g (about 86.7% of theory) of N-(2,4)6-trimethylphenyl-acetyl)-sarcosine methyl ester are obtained in the form of a pale yellow oil.

¹ H-NMR(200 MHz, CDCl₃): δ=2.18, 2 2, 2 28 (s, 9H Ar-CH₃); 3.0, 3.2 (s, 3H, NCH₃), 3.64, 3.67 (s, 2H, CH₂ -Ar), 3.66, 3.69 (s, 3H, OCH₃), 3.79, 4.14 (s, 2H, N-CH₂ -CO), 6.82 (s, 2H, Ar 3-H, 5-H)

EXAMPLE III ##STR443##

17.4 g (0.12 mol}of N-isopropylglycine ethyl ester are dissolved in 180 ml of absolute THF and 16.8 ml (0.12 mol) of triethylamine are added. 26.82 g (0.12 mol) of 2,6-dichlorophenylacetyl chloride in 20 ml of absolute THF are added dropwise at 0°-10° C. After 1 hour the mixture is stirred into 1 l of ice water +100 ml of 1 N/HCl,the product is extracted with CH₂ Cl₂ and the organic phase is dried and concentrated by evaporation. 36.8 g (89.1% of theory) of a yellow oil are obtained.

¹ H-NMR(200 MHz, CDCl₃): δ=1.11-1.32 (m, 9H CH₂ -CH₃ CH(CH₃)₂), 7.08-7.15 (1H, m, Ar 4-H), 7.25-7.32 (m, 2H, Ar-3-H, 5-H).

Crystallization from ether/n-hexane gives 3.8 g (80.4% of theory) of 4-(pivaloyloxy)-3-(2,4,6-trimethyl-phenyl)-1-methyl-3-pyrrolin-2-one of melting point 75° C.

The active compounds are suitable for combating animal pests, preferably arthropods and nematodes, in particular insects and arachnida encountered in agriculture, in forestry, in the protection of stored products and of materials, and in the hygiene field. They are active against normally sensitive and resistant species and against all or some stages of development. The abovementioned pests include:

From the order of the Isopoda, for example, Oniscus asellus, Armadillidium vulgare and Porcellio scaber. From the order of the Diplopoda, for example, Blaniulus guttulatus. From the order of the Chilopoda, for example, Geophilus carpophagus and Scutigera spec. From the order of the Symphyla, for example, Scutigerella immaculata. From the order of the Thysanura, for example, Lepisma saccharina. From the order of the Collembola, for example, Onychiurus armatus. From the order of the Orthoptera, for example, Blatta orientalis, Periplaneta americana, Leucophaea maderae, Blattella germanica, Acheta domesticus, Gryllotalpa spp., Locusta migratoria migratorioides, Melanoplus differentialis and Schistocerca gregaria. From the order of the Dermaptera, for example, Forficula auricularia. From the order of the Isoptera, for example, Reticulitermes spp.. From the order of the Anoplura, for example, Phylloxera vastatrix, Pemphigus spp., Pediculus humanus corporis, Haematopinus spp. and Linognathus spp. From the order of the Mallophaga, for example, Trichodectes spp. and Damalinea spp. From the order of the Thysanoptera, for example, Hercinothrips femoralis and Thrips tabaci. From the order of the Heteroptera, for example, Eurygaster spp., Dysdecus intermedius, Piesma quadrata, Cimex lectularius, Rhodnius prolixus and Triatoma spp. From the order of the Homoptera, for example, Aleurodes brassicae, Bemisia tabaci, Trialeurodes vaporariorum, Aphis gossypii, Brevicoryne brassicae, Cryptomyzus ribis, Aphis fabae, Doralis pomi, Eriosoma lanigerum, Hyalopterus arundinis, Macrosiphum avenae, Myzus spp., Phorodon humuli, Rhopalosiphum padi, Empoasca spp., Euscelis bilobatus, Nephotettix cincticeps, Lecanium corni, Saissetia oleae, Laodelphax striatellus, Nilaparvata lugens, Aonidiella aurantii, Aspidiotus hederae, Pseudococcus spp. and Psylla spp. From the order of the Lepidoptera, for example, Pectinophora gossypiella, Bupalus piniarius, Cheimatobia brumata, Lithocolletis blancardella, Hyponomeuta padella, Plutella maculipennis, Malacosoma neustria, Euproctis chrysorrhoea, Lymantria spp. Bucculatrix thurberiella, Phyllocnistis citrella, Agrotis spp., Euxoa spp., Feltia spp., Earias insulana, Heliothis spp., Spodoptera exigua, Mamestra brassicae, Panolis flammea, Prodenia litura, Spodoptera spp., Trichoplusia ni, Carpocapsa pomonella, Pieris spp., Chilo spp., Pyrausta nubilalis, Ephestia kuehniella, Galleria mellonella, Tineola bisselliella, Tinea pellionella, Hofmannophila pseudospretella, Cacoecia podana, Capua reticulana, Choristoneura fumiferana, Clysia ambiguella, Homona magnanima and Tortrix viridana. From the order of the Coleoptera, for example, Anobium punctatum, Rhizopertha dominica, Acanthoscelides obtectus, Acanthoscelides obtectus, Hylotrupes bajulus Agelastica alni, Leptinotarsa decemlineata, Phaedon cochleariae, Diabrotica spp., Psylliodes chrysocephala, Epilachna varivestis, Atomaria spp., Oryzaephilus surinamensis, Anthonomus spp., Sitophilus spp., Otiorrhynchus sulcatus, Cosmopolites sordidus, Ceuthorrhynchus assimilis, Hypera postica, Dermestes spp., Trogoderma spp., Anthrenus spp., Attagenus spp., Lyctus spp., Meligethes aeneus, Ptinus spp., Niptus, hololeucus, Gibbium psylloides, Tribolium spp., Tenebrio molitor, Agriotes spp., Conoderus spp., Melolontha melolontha, Amphimallon solstitialis and Costelytra zealandica. From the order of the Hymenoptera, for example, Diprion spp., Hoplocampa spp., Lasius spp., Monomorium pharaonis and Vespa spp. From the order of the Diptera, for example, Aedes spp., Anopheles spp., Culex spp., Drosophila melanogaster, Musca spp., Fannia spp., Calliphora erythrocephala, Lucilia spp., Chrysomyia spp., Cuterebra spp., Gastrophilus spp., Hyppobosca spp., Stomoxys spp., Oestrus spp., Hypoderma spp., Tabanus spp., Tannia spp., Bibio hortulanus, Oscinella frit, Phorbia spp., Pegomyia hyoscyami, Ceratitis capitata, Dacus oleae and Tipula paludosa.

From the order of the Siphonaptera, for example, Xenopsylla cheopis and Ceratophyllus spp. From the order of the Arachnida, for example, Scorpio maurus, Latrodectus mactans.

From the order of the Acarina, for example Acarus siro, Argas spp., Ornithodoros spp., Dermanyssus gallinae, Eriophyes ribis, Phyllocoptruta oleivora, Boophilus spp., Rhipicephalus spp., Amblyomma spp., Hyalomma spp., Ixodes spp., Psoroptes spp., Chorioptes spp., Sarcoptes spp., Tarsonemus spp., Bryobia praetiosa, Panonychus spp. and Tetranychus spp..

The phytoparasitic nematodes include Pratylenchus spp., Radopholus similis, Ditylenchus dipsaci, Tylenchulus semipenetrans, Heterodera spp., Meloidogyne spp., Aphelenchoides spp., Longidorus spp., Xiphenema spp. and Trichodorus spp..

The active compounds according to the invention can furthermore be used as defoliants, desiccants, agents for destroying broad-leaved plants and, especially, as weed-killers. By weeds, in the broadest sense, there are to be understood all plants which grow in locations where they are undesired. Whether the substances according to the invention act as total or selective herbicides depends essentially on the amount used.

It is characteristic of the compounds according to the invention that they have a selective effect against monocotyledon weeds when used in the pre-and postemergence method, combined with a good tolerance by crop plants.

The active compounds according to the invention can be used, for example, in connection with the following plants:

Monocotyledon weeds of the genera: Echinochloa, Setaria, Panicum, Digitaria, Phleum, Poa, Festuca, Eleusine, Brachiaria, Lolium, Bromus, Avena, Cyperus, Sorghum, Agropyron, Cynodon, Monochoria, Fimbristylis, Sagittaria, Eleocharis, Scirpus, Paspalum, Ischaemum, Sphenoclea, Dactyloctenium, Agrostis, Alopecurus and Apera.

Monocotyledon cultures of the genera: Oryza, Zea, Triticum, Hordeum, Avena, Secale, Sorghum, Panicum, Saccharum, Ananas, Asparagus and Allium.

However, the use of the active compounds according to the invention is in no way restricted to these genera, but also extends in the same manner to other plants.

The compounds are suitable, depending on the concentration, for the total combating of weeds, for example on industrial terrain and rail tracks, and on paths and squares with or without tree plantings. Equally, the compounds can be employed for combating weeds in perennial cultures, for example afforestations, decorative tree plantings, orchards, vineyards, citrus groves, nut orchards, banana plantations, coffee plantations, tea plantations, rubber plantations, oil palm plantations, cocoa plantations, soft fruit plantings and hopfields, and for the selective combating of weeds in annual cultures.

Here, the compounds according to the invention show a good tolerance by important crop plants, such as, for example, wheat, cotton, soy beans, citrus fruit and sugar beets, besides having an excellent action against harmful plants, and they can therefore be employed as selective weedkillers.

The active compounds can be converted into the customary formulations, such as solutions, emulsions, suspensions, powders, foams, pastes, granules, aerosols, natural and synthetic materials impregnated with active compound, and very fine capsules in polymeric substances and in coating compositions for seeds, furthermore in formulations using burning equipment such as fumigating cartridges, cans, coils,etc., and in ULV cold mist and warm mist formulations.

These formulations are produced in a known manner, for example by mixing the active compounds with extenders, that is liquid solvents, liquefied gases under pressure and/or solid carriers, optionally with the use of surface-active agents, that is emulsifying agents and/or dispersing agents and/or foam-forming agents. In the case of the use of water as an extender, organic solvents can, for example, also be used as auxiliary solvents. As liquid solvents, there are suitable in the main: aromatics, such as xylene, toluene or alkylnaphthalenes, chlorinated aromatics and chlorinated aliphatic hydrocarbons, such as chlorobenzenes, chloroethylenes or methylene chloride, aliphatic hydrocarbons, such as cyclohexane or paraffins, for example petroleum fractions, alcohols, such as butanol or glycol as well as their ethers and esters, ketones, such as acetone, methyl ethyl ketone, methyl isobutyl ketone or cyclohexanone, strongly polar solvents, such as dimethylformamide and dimethyl sulphoxide, as well as water; liquefied gaseous extenders or carriers are those liquids which are gaseous at normal temperature and under atmospheric pressure, for example aerosol propellant, such as halogenohydrocarbons as well as butane, propane, nitrogen or carbon dioxide. As solid carriers there are suitable: for example ground natural minerals, such as kaolins, clays, talc, chalk, quartz, attapulgite, montmorillonite or diatomaceous earth, and ground synthetic minerals, such as highly disperse silica, alumina and silicates, as solid carriers for granules there are suitable: for example crushed and fractionated natural rocks such as calcite, marble, pumice, sepiolite and dolomite, as well as synthetic granules of inorganic and organic meals, and granules of organic material such as sawdust, coconut shells, corn cobs and tobacco stalks; as emulsifying and/or foam-forming agents there are suitable: for example non-ionic and anionic emulsifiers, such as polyoxyethylene fatty acid esters, polyoxyethylene fatty alcohol ethers, for example alkylaryl polyglycol ethers, alkylsulphonates, alkyl sulphates, arylsulphcnates as well as albumin hydrolysis products; as dispersing agents there are suitable: for example lignin-sulphite waste liquors and methylcellulose.

Adhesives such as carboxymethylcellulose and natural and synthetic polymers in the form of powders, granules or latexes, such as gum arabic, polyvinyl alcohol and polyvinyl acetate, as well as natural phospholipids, such as cephalins and lecithins, and synthetic phospholipids, can be used in the formulations. Further additives can be mineral and vegetable oils.

It is possible to use colorants such as inorganic pigments, for example iron oxide, titanium oxide and Prussian Blue, and organic dyestuffs, such as alizarin dyestuffs, azo dyestuffs and metal phthalocyanine dyestuffs, and trace nutrients such as salts of iron, manganese, boron, copper, cobalt, molybdenum and zinc.

The formulations in general contain between 0.1 and 95 percent by weight of active compound, preferably between 0.5 and 90%.

The active compounds according to the invention can be present in their commercially available formulations and in the use forms, prepared from these formulations, as a mixture with other active compounds, such as insecticides, attractants, sterilizing agents, acaricides, nematicides, herbicides or fungicides. The insecticides include, for example, phosphates, carbamates, carboxylates, chlorinated hydrocarbons, phenylureas and substances produced by microorganisms, inter alia.

The active compounds according to the invention can furthermore be present in their commercially available formulations and in the use forms, prepared from these formulations, as a mixture with synergistic agents. Synergistic agents are compounds which increase the action of the active compounds, without it being necessary for the synergistic agent added to be active itself.

The active compound content of the use forms prepared from the commercially available formulations can vary within wide limits. The active compound concentration of the use forms can be from 0.0000001 to 95% by weight of active compound, preferably between 0.0001 and 1% by weight.

The compounds are employed in a customary manner appropriate for the use forms.

The active compounds which can be used according to the invention are also suitable for combating midges, ticks,etc.,in the sectors of animal keeping and cattle breeding; better results, for example higher milk production, greater weight, more attractive animal pelt, longer life,etc., can be achieved by combating the pests.

The application of the active compounds which can be used according to the invention occurs in this sector in a known fashion, such as by oral application in the form of, for example, tablets, capsules, potions, granules, by means of dermal or external application in the form of, for example, dipping, spraying, pouring-on, spotting-on and dusting, as well as by means of parenteral application in the form, for example, of injection, and, furthermore, by means of the feed-through process. In addition, application as molded articles (collar, ear tag) is also possible.

EXAMPLE A Nephotettix test

Solvent: 7 parts by weight of dimethyl formamide

Emulsifier: 1 part by weight of alkylaryl polyglycol ether

To produce a suitable preparation of active compound, I part by weight of active compound is mixed with the stated amount of solvent and the stated amount of emulsifier, and the concentrate is diluted to the desired concentration with water.

Rice seedlings (oryza sativa) are treated by being dipped into the preparation of active compound at the desired concentration, and larvae of the green rice leaf hopper (Nephotettix cincticeps) are placed on the seedlings while they are still wet.

After the desired time, destruction is determined in %. 100% denotes here that all the leaf hoppers have been destroyed; 0% denotes that none of the leaf hoppers have been destroyed.

In this test, for example the following compounds of the Preparation Examples show a superior activity compared with the prior art: (5), (54), (55), (56), (57), (58).

The compounds of the formula (I) according to the invention show antimicrobial, and particularly powerful antibacterial and antimycotic, actions. They have a very broad range of antimycotic actions, in particular against dermatophytes and yeasts, as well as biphasic fungi, for example against Candida species, such as Candida albicans, Epidermophyton species, such as Epidermophyton floccosum, Aspergillus species, such as Aspergillus niger and Aspergillus fumigatus, Trichophyton species, such as Trichophyton mentagrophytes, Microsporon species, such as Microsporon felineum, as well as Torulopsis species, such as Torulopsis glabrata. This list of microorganisms in no way intends to limit the germs which can be combated, but only serves for illustration.

Examples of indication in human medicine which may be mentioned are: Dermatomycoses and systemic mycoses caused by Trichophyton mentagrophytes and other Trichophyton species, Microsporon species as well as Epidermophyton floccosum, yeasts and biphasic fungi, as well as molds.

The following may be mentioned as examples of a field of indication in veterinary medicine:

All dermatomycoses and systemic mycoses, in particular those caused by the abovementioned pathogens.

The present invention includes pharmaceutical preparations which, besides non-toxic, inert pharmaceutically suitable excipients, contain one or more active compounds according to the invention, or which consist of one or more active compounds according to the invention.

The present invention also includes pharmaceutical preparations in dosage units. This means that the preparations are in the form of individual parts, for example tablets, coated tablets, capsules, pills, suppositories and ampoules, whose active compound content corresponds to a fraction, or a multiple, of a single dose. The dosage units can contain, for example, 1, 2, 3 or 4 simple doses or 1/2, 1/3 or 1/4 of a simple dose. A single dose preferably contains the amount of active compound which is administered during one application, and which usually corresponds to a whole, half, a third, or a quarter of a daily dose.

Non-toxic, inert pharmaceutically suitable excipients are taken to mean solid, semi-solid or liquid diluents, fillers or formulation auxiliaries of any type. Preferred pharmaceutical preparations which may be mentioned are tablets, coated tablets, capsules, pills, granules, suppositories, solutions, suspensions and emulsions, pastes, ointments, gels, creams, lotions, powders or sprays.

Tablets, coated tablets, capsules, pills and granules can contain the active compound(s) besides conventional excipients, such as (a) fillers and extenders, for example starches, lactose, sucrose, glucose, mannitol and silicic acid, (b) binders, for example carboxymethylcellulose, alginates, gelantine, polyvinyl pyrrolidone, (c) humectants, for example glycerol, (d) disintegrants, for example agar-agar, calcium carbonate and sodium bicarbonate, (e) solution retardants, for example paraffin and (f) resorption accelerators, for example quaternary ammonium compounds, (g) wetting agents, for example cetyl alcohol and glycerol monostearate, (h) adsorption agents, for example kaolin and bentonite and (i) lubricants, for example talc, calcium stearate and magnesium stearate and solid polyethylene glycols, or mixtures of the substances listed under (a) to (i).

The tablets, coated tablets, capsules, pills and granules may be provided with the conventional coatings and shells, optionally containing opacifying agents, and they can be composed in a manner such that they release the active compound(s) only, or preferably, in a specific part of the intestinal tract, if appropriate in a retarded manner, suitable embedding compositions which can be used being, for example, polymeric substances and waxes.

The active compound(s) can also be present in microencapsulated form, if appropriate together with one or more of the abovementioned excipients.

Suppositories can contain, besides the active compound(s), the conventional water-soluble or water-insoluble excipients, for example polyethylene glycols, fats, for example cocoa fat, and higher esters (for example C₁₄ -alcohol with C₁₆ -fatty acid), or mixtures of these substances.

Ointments, pastes, creams and gels can contain, besides the active compound(s), the conventional excipients, for example animal and vegetable fats, waxes, paraffins, starch, tragacanth, cellulose derivatives, polyethylene glycols, silicones, bentonites, silicic acid, talc and zinc oxide, or mixtures of these substances.

Powders and sprays can contain, besides the active compound(s), the conventional excipients, for example lactose, talc, silicic acid, aluminium hydroxide, calcium silicate and polyamide powder, or mixtures of these substances, and sprays can additionally contain the conventional propellants, for example chlorofluorohydrocarbons.

Solutions and emulsions can contain, besides the active compound(s), the conventional excipients, such as solvents, solution retardants and emulsifiers, for example water, ethyl alcohol, isopropyl alcohol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene glycol, 1,3-butylene glycol, dimethyl formamide, oils, in particular cottonseed oil, groundnut oil, corn germ oil, olive oil, castor oil and sesame seed oil, glycerol, glycerol formal, tetrahydrofurfuryl alcohol, polyethylene glycols and fatty acid esters of sorbitan, or mixtures of these substances.

For parenteral application, the solutions and emulsions can also be in sterile form and a form isotonic which is with blood.

Suspensions can contain, besides the active compound(s), the conventional excipients, such as liquid diluents, for example water, ethyl alcohol, propyl alcohol, suspending agents, for example ethoxylated isostearyl alcohols, polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester, microcrystalline cellulose, aluminium metahydroxide, bentonite, agar-agar and tragacanth, or mixtures of these substances.

The formulation types mentioned can also contain colourants, preservatives and additives which improve the odour and flavour, for example peppermint oil and eucalylptus oil, and sweeteners, for example saccharin.

The therapeutically active compounds in the abovementioned pharmaceutical preparations should preferably be present in a concentration of about 0.1 to 99.5, preferably of 0.5 to 95%, by weight of the total mixture.

In addition to the active compounds according to the invention, the abovementioned pharmaceutical preparations can also contain other pharmaceutical active compounds.

The preparation of the abovementioned pharmaceutical preparations is carried out in a customary manner by known methods, for example by mixing the active compound(s) with the excipient(s).

The present invention also includes the use of the active compounds according to the invention, as well as the use of pharmaceutical preparations which contain one or more active compounds according to the invention, in human and veterinary medicine for the prevention, ease and/or cure of the abovementioned diseases.

The active substances or the pharmaceutical preparations can be administered locally, orally, parenterally, intraperitoneally and/or rectally, preferably parenterally, in particular intravenously.

In general, it has proven advantageous both in human and in veterinary medicine, to administer the active compound(s) according to the invention in total amounts of about 2.5 to about 200, preferably of 5 to 150, mg/kg of body weight every 24 hours, where appropriate in the form of several individual doses, in order to achieve the desired results.

In the case of oral administration, the active compounds according to the invention are administered in total amounts of about 2.5 to about 200, preferably of 5 to 150, mg/kg of body weight every 24 hours, and in the case of parenteral application in total amounts of about 2.5 to about 50, preferably from 1 to 25, mg/kg of body weight every 24 hours.

However, it may be necessary to deviate from the dosages mentioned, namely as a function of the species and the bodyweight of the object to be treated, the type and severity of the disease, the type of preparation and the way the medicament is administered, as well as of the period or interval within which the medicament is administered. Thus, in some cases it may suffice to use less than the abovementioned amount of active compound, while in other cases the abovementioned amount of active compound must be exceeded. The decision concerning the specific optimum dosage required and the way in which the active compounds are administered can easily be made by anyone skilled in the art on the basis of his expert knowledge.

EXAMPLE B Antimycotic in-vitro activity

Experimental set-up:

The in-vitro tests were carried out using inocula of an average of 1×10⁴ microorganisms/ml of substrate. The nutrient medium used was Yeast Nitrogen Base medium for yeasts and Kimmig medium for moulds and dermatophytes.

The incubation temperature was 37° C. in the case of yeasts and 28° C. in the case of moulds and dermatophytes, the incubation time was 24 to 96 hours in the case of yeasts and 96 to 120 hours in the case of dermatophytes and moulds.

The fungicides were assessed by plating and reincubation of fully inhibited batches, fungicidal concentrations being those containing fewer than 100 microorganisms c.f.n. (colony-forming unit) per ml.

In this test, the compounds of the formula (I) according to the invention of Preparation Examples 45, 46, 47 showed a highly pronounced antimycotic activity.

It is understood that the specification and examples are illustrative but not limitative of the present invention and that other embodiments within the spirit and scope of the invention will suggest themselves to those skilled in the art. In the following claims, substituent "C*" is expressed as D. 

We claim:
 1. A method combating unwanted vegetation which comprises applying thereto or to a locus from which it is desired to exclude such vegetation, a herbicidally effective amount of a 3-aryl-pyrrolidine-2,4-dione of the formula ##STR444## in which X represents C₁ -C₆ -alkyl, halogen or C₁ -C₆ -alkoxy,Y represents hydrogen, C₁ -C₆ -alkyl, halogen, C₁ -C₆ -alkoxy or (C₁ -C₃)-halogenoalkyl, Z represents C₁ -C₆ -alkyl, halogen or C₁ -C₆ -alkoxy, n represents a number from 0-3, R represents hydrogen (Ia) or represents the groups of the formula

    --CO--R.sup.1 or --CO--O--R.sup.2,

in whichR¹ represents C₁ -C₂₀ -alkyl, C₂ -C₂₀ -alkenyl, C₁ -C₈ -alkoxy-C₂ -C₈ -alkyl, C₁ -C₈ -alkylthio-C₂ -C₈ -alkyl, C₁ -C₈ -polyalkoxy-C₂ -C₈ -alkyl or cycloalkyl which has 3-8 ring atoms and which can be interrupted by oxygen and/or sulphur, each of which radicals is optionally substituted by halogen, or represents phenyl which is optionally substituted by halogen, or represents phenyl which is optionally substituted by halogen, nitro, C₁ -C₆ -alkyl, C₁ -C₆ -alkoxy, C₁ -C₆ -halogenoalkyl or C₁ -C₆ -halogenoalkoxy, or represents phenyl-C₁ -C₆ -alkyl which is optionally substituted by halogen, C₁ -C₆ -alkyl, C₁ -C₆ -alkoxy, C₁ -C₆ -halogenoalkyl or C₁ -C₆ -halogenoalkoxy, R² represents C₁ -C₂₀ -alkyl, C₂ -C₂₀ -alkenyl, C₁ -C₈ -alkoxy-C₂ -C₈ -alkyl or C₁ -C₈ -polyalkoxy-C₂ -C₈ -alkyl, each of which radicals is optionally substituted by halogen, or represents phenyl or cycloalkyl which has 3-8 ring atoms, each of which radicals is optionally substituted by halogen, nitro, C₁ -C₆ -alkyl, C₁ -C₆ -alkoxy or C₁ -C₆ -halogenoalkyl, A represents straight-chain or branched C₁ -C₁₂ -alkyl, C₃ -C₈ -alkenyl, C₃ -C₈ -alkinyl, C₁ -C₁₀ -alkoxy-C₂ -C₈ -alkyl, C₁ -C₈ -polyalkoxy-C₂ -C₈ -alkyl, C₁ -C₁₀ -alkylthio-C₂ -C₈ -alkyl or cycloalkyl which has 3-8 ring atoms and which can be interrupted by oxygen and/or sulphur, each of which radicals is optionally substituted by halogen, or represents aryl-C₁ -C₆ -alkyl which is optionally substituted by halogen, C₁ -C₆ -alkyl-C₁ -C₆ -haloalkyl, C₁ -C₆ -alkoxy or nitro, and B and D independently of one another represent hydrogen, straight-chain or branched C₁ -C₁₂ -alkyl or C₁ -C₈ -alkoxyalkyl.
 2. A method according to claim 1, in whichX represents C₁ -C₄ -alkyl, halogen or C₁ -C₄ -alkoxy, Y represents hydrogen, C₁ -C₆ -alkyl, halogen, C₁ -C₄ -alkoxy or C₁ -C₂ -halogenoalkyl, Z represents C₁ -C₄ -alkyl, halogen or C₁ -C₄ -alkoxy, n represents a number from 0-3 R represents hydrogen or represents the groups of the formula

    --CO--R.sup.1 or --CO--O--R.sup.2,

in whichR¹ represents C₁ -C₁₆ -alkyl, C₂ -C₁₆ -alkenyl, C₁ -C₆ -alkoxy-C₂ -C₆ -alkyl, C₁ -C₆ -alkylthio-C₂ -C₆ -alkyl, C₁ -C₆ -polyalkoxy-C₂ -C₆ -alkyl or cycloalkyl which has 3-7 ring atoms and which can be interrupted by 1-2 oxygen and/or sulphur atoms, each of which radicals is optionally substituted by halogen, or represents phenyl which is optionally substituted by halogen, nitro, C₁ -C₄ -alkyl, C₁ -C₄ -alkoxy, C₁ -C₃ -halogenoalkyl or C₁ -C₃ -halogenoalkoxy, or represents phenyl-C₁ -C₄ -alkyl which is optionally substituted by halogen, C₁ -C₄ -alkyl, C₁ -C₄ -alkoxy, C₁ -C₃ -halogenoalkyl or C₁ -C₃ -halogenoalkoxy, or represents hetaryl which is optionally substituted by halogen or C₁ -C₆ -alkyl, or represents phenoxy-C₁ -C₅ -alkyl which is optionally substituted by halogen or C₁ -C₄ -alkyl, R² represents C₁ -C₁₆ -alkyl, C₂ -C₁₆ -alkenyl, C₁ -C₁₆ -alkoxy-C₂ -C₆ -alkyl or C₁ -C₆ -polyalkoxy-C₂ -C₆ -alkyl, each of which radicals is optionally substituted by halogen or represents phenyl or cycloalkyl which has 3-7 ring atoms, each of which radicals is optionally substituted by halogen, nitro, C₁ -C₄ -alkyl, C₁ -C₃ -alkoxy or C₁ -C₃ -halogenoalkyl, A represents straight-chain or branched C₁ -C₁₀ -alkyl, C₃ -C₆ -alkenyl, C₃ -C₆ -alkinyl, C₁ -C₆ -alkoxy-C₂ -C₆ -alkyl, C₁ -C₆ -polyalkoxy-C₂ -C₆ -alkyl, C₁ -C₈ -alkylthio-C₂ -C₆ -alkyl or cycloalkyl which has 3-7 ring atoms and which can be interrupted by 1-2 oxygen and/or sulphur atoms, each of which radicals is optionally substituted by halogen, or represents aryl-C₁ -C₄ -alkyl which is optionally substituted by halogen, C₁ -C₄ -alkyl, C₁ -C₄ -halogenoalkyl-C₁ -C₄ -alkoxy or nitro, and B and C* independently of one another represent hydrogen, straight-chain or branched C₁ -C₁₀ -alkyl or C₁ -C₆ -alkoxyalkyl.
 3. A method according to claim 1, in whichX represents methyl, ethyl, propyl, i-propyl, fluorine, chlorine, bromine, methoxy or ethoxy, Y represents hydrogen, methyl, ethyl, propyl, i-propyl, butyl, i-butyl, tert.-butyl, fluorine, chlorine, bromine, methoxy, ethoxy or trifluoromethyl, Z represents methyl, ethyl, i-propyl, butyl, i-butyl, tert.-butyl, fluorine, chlorine, bromine, methoxy or ethoxy, n represents a number from 0-3, R represents hydrogen or represents the groups of the formula

    --CO--R.sup.1 or --CO--O--R.sup.2,

in whichR¹ represents C₁ -C₁₄ -alkyl, C₂ -C₁₄ -alkenyl, C₁ -C₄ -alkoxy-C₂ -C₆ -alkyl, C₁ -C₄ -alkylthio-C₂ -C₆ -alkyl, C₁ -C₄ -polyalkoxyl-C₂ -C₄ -alkyl or cycloalkyl which has 3-6 ring atoms and which can be interrupted by 1-2 oxygen and/or sulphur atoms, each of which radicals is optionally substituted by fluorine or chlorine, or represents phenyl which is optionally substituted by fluorine, chlorine, bromine, methyl, ethyl, propyl, i-propyl, methoxy, ethoxy, trifluoromethyl, trifluoromethoxy or nitro, or represents phenyl-C₁ -C₃ -alkyl which is optionally substituted by fluorine, chlorine, bromine, methyl, ethyl, propyl, i-propyl, methoxy, ethoxy, trifluoromethyl or trifluoromethoxy, or represents phenoxy-C₁ -C₄ -alkyl which is optionally substituted by fluorine, chlorine, methyl or ethyl, R² represents C₁ -C₁₄ -alkyl, C₂ -C₁₄ -alkenyl, C₁ -C₄ -alkoxy-C₂ -C₆ -alkyl or C₁ -C₄ -polyalkoxy-C₂ -C₆ -alkyl, each of which radicals is optionally substituted by fluorine or chlorine, or represents phenyl or cycloalkyl which has 3-6 ring atoms, each of which radicals is optionally substituted by fluorine, chlorine, nitro, methyl, ethyl, propyl, i-propyl, methoxy, ethoxy or trifluoromethyl, A represents straight-chain or branched C₁ -C₈ -alkyl, C₃ -C₄ -alkenyl, C₃ -C₄ -alkinyl, C₁ -C₆ -alkoxy-C₂ -C₄ -alkyl, C₁ -C₄ -polyalkoxy-C₂ -C₄ -alkyl, C₁ -C₆ -alkylthio-C₂ -C₄ -alkyl or cycloalkyl which has 3-6 ring atoms and which can be interrupted by 1-2 oxygen and/or sulphur atoms, each of which radicals is optionally substituted by halogen, or represents aryl-C₁ -C₃ -alkyl which is optionally substituted by fluorine, chlorine, bromine, methyl, ethyl, propyl, isopropyl, methoxy, ethoxy, trifluoromethyl or nitro, and B and C* independently of one another represent hydrogen, straight-chain or branched C₁ -C₈ -alkyl and C₁ -C₄ -alkoxyalkyl.
 4. A method according to claim 1, wherein such compound is 3-(2,6-dichlorophenyl)-1-methyl-pyrrolidine-2,4-dione of the formula ##STR445##
 5. A method according to claim 1, wherein such compound is 3-(2,4,6-trimethylphenyl)-1-(1,2,2-trimethylpropyl)-pyrrolidine-2,4-dione of the formula ##STR446##
 6. A method according to claim 1, wherein such compound is 3-(2,4,6-trimethylphenyl)-1-(1,1,3,3-tetramethyl-butyl)-pyrrolidine-2,4-dione of the formula ##STR447##
 7. A method according to claim 1, wherein such compound is 3-(2,4,6-trimethylphenyl)-1-allyl-pyrrolidine-2,4-dione of the formula ##STR448##
 8. A method according to claim 1, wherein such compound is 3-(2,4,6-trimethylphenyl)-1-cyclopropyl-5,5-dimethyl-pyrollidine-2,4-dione of the formula ##STR449##
 9. A method according to claim 1, wherein such compound is 3-(2,4,6-trimethylphenyl)-1-cyclopentyl-pyrrollidine-2,4-dione of the formula ##STR450##
 10. A method according to claim 1, wherein such compound is 3-(2,4,6-trimethylphenyl)-1-cyclopentyl-5-methyl-pyrrolidine-2,4-dione of the formula ##STR451##
 11. A method according to claim 1, wherein such compound is 3-(2,4,6-trimethylphenyl)-1-cyclopentyl-5-ethyl-pyrrolidine-2,4-dione of the formula ##STR452##
 12. A method according to claim 1, wherein such compound is 3-(2,4,6-trimethylphenyl)-1-cyclopentyl-5-propyl-pyrrolidine-2,4-dione of the formula ##STR453## 